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- W2045472712 endingPage "48" @default.
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- W2045472712 abstract "Systemic lupus erythematosus (SLE) is a female predominant autoimmune disease characterized by multi-organ disorders. The pathogenesis of SLE is complex. Corticosteroids and immunosuppressive drugs are widely used to treat patients with SLE. However, these indiscriminate suppressors of the immune-mediated inflammatory aberration treat SLE at the cost of considerable adverse effects. Undoubtedly, there is a need for safer and more effective treatments for SLE. Cell-based therapies, although very much in their infancy, are of increasing interest in the treatment of SLE due to their potential for long-term suppression or a possible cure of the disease. Several immunoregulatory cell types, including regulatory T cells, mesenchymal stem cells, B-cells and natural killer cells, have recently been developed as novel products for tolerance-promoting therapies. Here, we provide a brief overview of current research of new cell-based therapeutic approaches that have undergone pre-clinical or clinical trials in the treatment of SLE." @default.
- W2045472712 created "2016-06-24" @default.
- W2045472712 creator A5054869745 @default.
- W2045472712 creator A5069298809 @default.
- W2045472712 creator A5072399728 @default.
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- W2045472712 date "2015-01-01" @default.
- W2045472712 modified "2023-10-15" @default.
- W2045472712 title "Cell-based therapies for systemic lupus erythematosus" @default.
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- W2045472712 doi "https://doi.org/10.1016/j.autrev.2014.10.001" @default.
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- W2045472712 hasPublicationYear "2015" @default.
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