Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045481316> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2045481316 abstract "In their multivariate analysis of the effect of serum lipoproteins on extracranial carotid artery atherosclerosis in the March 1991 issue of the Mayo Clinic Proceedings (pages 259267), Homer and associates did not report on measuring serum lipoprotein (a) [Lp(a)]. This low-density lipoprotein-like particle contains, in addition to apoprotein B-100, the unique glycoprotein apolipoprotein (a). 1 Discovery of the striking structural homology between apolipoprotein (a) and human plasminogen 1 has stimulated intensive investigation of Lp(a) as a possible link between atherosclerosis and thrombosis. 1,2 Recent studies have shown that Lp(a) can bind fibrin, inhibit tissue plasminogen activator-fibrin binding, suppress plasminogen activation by tissue plasminogen activator, and competitively inhibit plasminogen binding to monocytoid cells, endothelial cells, tetranectin, and thrombospondin. 2 This in vitro evidence of interference with normal fibrinolytic mechanisms supports a role for Lp(a) in promoting thrombosis. Native Lp(a) and recombinant apolipoprotein (a) can bind to macrophages through a specific high-affinity receptor; 3 the result is the intracellular accumulation of cholesterol. These data demonstrate a mechanism for formation of atheromatous foam cells by Lp(a), in addition to its thrombogenic potential." @default.
- W2045481316 created "2016-06-24" @default.
- W2045481316 creator A5008205347 @default.
- W2045481316 creator A5040093844 @default.
- W2045481316 date "1992-03-01" @default.
- W2045481316 modified "2023-10-17" @default.
- W2045481316 title "Serum Lipoprotein (a) as a Risk Factor for Extracranial Carotid Artery Atherosclerosis" @default.
- W2045481316 cites W1977734748 @default.
- W2045481316 cites W1992992795 @default.
- W2045481316 cites W1998643913 @default.
- W2045481316 cites W2019600329 @default.
- W2045481316 cites W2051267797 @default.
- W2045481316 cites W2058129900 @default.
- W2045481316 cites W2067318301 @default.
- W2045481316 cites W2133778284 @default.
- W2045481316 cites W2408232787 @default.
- W2045481316 cites W3147533580 @default.
- W2045481316 doi "https://doi.org/10.1016/s0025-6196(12)60111-6" @default.
- W2045481316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1545600" @default.
- W2045481316 hasPublicationYear "1992" @default.
- W2045481316 type Work @default.
- W2045481316 sameAs 2045481316 @default.
- W2045481316 citedByCount "2" @default.
- W2045481316 crossrefType "journal-article" @default.
- W2045481316 hasAuthorship W2045481316A5008205347 @default.
- W2045481316 hasAuthorship W2045481316A5040093844 @default.
- W2045481316 hasBestOaLocation W20454813161 @default.
- W2045481316 hasConcept C126322002 @default.
- W2045481316 hasConcept C134018914 @default.
- W2045481316 hasConcept C164144092 @default.
- W2045481316 hasConcept C170493617 @default.
- W2045481316 hasConcept C195687474 @default.
- W2045481316 hasConcept C203014093 @default.
- W2045481316 hasConcept C2776104379 @default.
- W2045481316 hasConcept C2776572282 @default.
- W2045481316 hasConcept C2778163477 @default.
- W2045481316 hasConcept C2779679481 @default.
- W2045481316 hasConcept C2780072125 @default.
- W2045481316 hasConcept C2780868729 @default.
- W2045481316 hasConcept C54173615 @default.
- W2045481316 hasConcept C62746215 @default.
- W2045481316 hasConcept C71924100 @default.
- W2045481316 hasConceptScore W2045481316C126322002 @default.
- W2045481316 hasConceptScore W2045481316C134018914 @default.
- W2045481316 hasConceptScore W2045481316C164144092 @default.
- W2045481316 hasConceptScore W2045481316C170493617 @default.
- W2045481316 hasConceptScore W2045481316C195687474 @default.
- W2045481316 hasConceptScore W2045481316C203014093 @default.
- W2045481316 hasConceptScore W2045481316C2776104379 @default.
- W2045481316 hasConceptScore W2045481316C2776572282 @default.
- W2045481316 hasConceptScore W2045481316C2778163477 @default.
- W2045481316 hasConceptScore W2045481316C2779679481 @default.
- W2045481316 hasConceptScore W2045481316C2780072125 @default.
- W2045481316 hasConceptScore W2045481316C2780868729 @default.
- W2045481316 hasConceptScore W2045481316C54173615 @default.
- W2045481316 hasConceptScore W2045481316C62746215 @default.
- W2045481316 hasConceptScore W2045481316C71924100 @default.
- W2045481316 hasLocation W20454813161 @default.
- W2045481316 hasLocation W20454813162 @default.
- W2045481316 hasOpenAccess W2045481316 @default.
- W2045481316 hasPrimaryLocation W20454813161 @default.
- W2045481316 hasRelatedWork W1968723265 @default.
- W2045481316 hasRelatedWork W1992753622 @default.
- W2045481316 hasRelatedWork W1993488426 @default.
- W2045481316 hasRelatedWork W2007199634 @default.
- W2045481316 hasRelatedWork W2030544707 @default.
- W2045481316 hasRelatedWork W2045481316 @default.
- W2045481316 hasRelatedWork W2087314277 @default.
- W2045481316 hasRelatedWork W2322900513 @default.
- W2045481316 hasRelatedWork W2399063111 @default.
- W2045481316 hasRelatedWork W3141700921 @default.
- W2045481316 isParatext "false" @default.
- W2045481316 isRetracted "false" @default.
- W2045481316 magId "2045481316" @default.
- W2045481316 workType "article" @default.