Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045484848> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2045484848 endingPage "693" @default.
- W2045484848 startingPage "687" @default.
- W2045484848 abstract "Abstract Amyloid plaques are one of the hallmarks of Alzheimer's disease (AD). This study evaluated a novel μMRI strategy based on “passive staining” of brain samples by gadoteric acid. The protocol was tested at 4.7T on control animals and APP/PS1 mice modeling AD lesions. T 1 was strongly decreased in passively stained brains. On high‐resolution 3D gradient echo images, the contrast between the cortex and subcortical structures was highly improved due to a T2* effect. The brains of APP/PS1 mice revealed plaques as hypointense spots. They appeared larger in long compared to short TE images. This suggests that, after passive staining, plaques caused a susceptibility effect. This easily performed protocol is a complementary method to classic histology to detect the 3D location of plaques. It may also be used for the validation of in vivo MRI protocols for plaque detection by facilitating registration with histology via post mortem MRI. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc." @default.
- W2045484848 created "2016-06-24" @default.
- W2045484848 creator A5003701057 @default.
- W2045484848 creator A5015051450 @default.
- W2045484848 creator A5015794600 @default.
- W2045484848 creator A5063954532 @default.
- W2045484848 date "2006-02-07" @default.
- W2045484848 modified "2023-10-13" @default.
- W2045484848 title "Passive staining: A novel ex vivo MRI protocol to detect amyloid deposits in mouse models of Alzheimer's disease" @default.
- W2045484848 cites W168886292 @default.
- W2045484848 cites W1978831666 @default.
- W2045484848 cites W1987883931 @default.
- W2045484848 cites W1989252530 @default.
- W2045484848 cites W2006805877 @default.
- W2045484848 cites W2007157911 @default.
- W2045484848 cites W2007284815 @default.
- W2045484848 cites W2022630760 @default.
- W2045484848 cites W2058448983 @default.
- W2045484848 cites W2072846848 @default.
- W2045484848 cites W2080516466 @default.
- W2045484848 cites W2087656882 @default.
- W2045484848 cites W2092677917 @default.
- W2045484848 cites W2142412936 @default.
- W2045484848 cites W2162319029 @default.
- W2045484848 doi "https://doi.org/10.1002/mrm.20810" @default.
- W2045484848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16470593" @default.
- W2045484848 hasPublicationYear "2006" @default.
- W2045484848 type Work @default.
- W2045484848 sameAs 2045484848 @default.
- W2045484848 citedByCount "36" @default.
- W2045484848 countsByYear W20454848482012 @default.
- W2045484848 countsByYear W20454848482013 @default.
- W2045484848 countsByYear W20454848482015 @default.
- W2045484848 countsByYear W20454848482016 @default.
- W2045484848 countsByYear W20454848482017 @default.
- W2045484848 countsByYear W20454848482018 @default.
- W2045484848 countsByYear W20454848482019 @default.
- W2045484848 countsByYear W20454848482021 @default.
- W2045484848 countsByYear W20454848482022 @default.
- W2045484848 crossrefType "journal-article" @default.
- W2045484848 hasAuthorship W2045484848A5003701057 @default.
- W2045484848 hasAuthorship W2045484848A5015051450 @default.
- W2045484848 hasAuthorship W2045484848A5015794600 @default.
- W2045484848 hasAuthorship W2045484848A5063954532 @default.
- W2045484848 hasConcept C126838900 @default.
- W2045484848 hasConcept C142724271 @default.
- W2045484848 hasConcept C143409427 @default.
- W2045484848 hasConcept C150903083 @default.
- W2045484848 hasConcept C169760540 @default.
- W2045484848 hasConcept C207001950 @default.
- W2045484848 hasConcept C26291073 @default.
- W2045484848 hasConcept C2777348757 @default.
- W2045484848 hasConcept C2777633098 @default.
- W2045484848 hasConcept C2779134260 @default.
- W2045484848 hasConcept C502032728 @default.
- W2045484848 hasConcept C57742111 @default.
- W2045484848 hasConcept C71924100 @default.
- W2045484848 hasConcept C74864618 @default.
- W2045484848 hasConcept C86803240 @default.
- W2045484848 hasConceptScore W2045484848C126838900 @default.
- W2045484848 hasConceptScore W2045484848C142724271 @default.
- W2045484848 hasConceptScore W2045484848C143409427 @default.
- W2045484848 hasConceptScore W2045484848C150903083 @default.
- W2045484848 hasConceptScore W2045484848C169760540 @default.
- W2045484848 hasConceptScore W2045484848C207001950 @default.
- W2045484848 hasConceptScore W2045484848C26291073 @default.
- W2045484848 hasConceptScore W2045484848C2777348757 @default.
- W2045484848 hasConceptScore W2045484848C2777633098 @default.
- W2045484848 hasConceptScore W2045484848C2779134260 @default.
- W2045484848 hasConceptScore W2045484848C502032728 @default.
- W2045484848 hasConceptScore W2045484848C57742111 @default.
- W2045484848 hasConceptScore W2045484848C71924100 @default.
- W2045484848 hasConceptScore W2045484848C74864618 @default.
- W2045484848 hasConceptScore W2045484848C86803240 @default.
- W2045484848 hasIssue "3" @default.
- W2045484848 hasLocation W20454848481 @default.
- W2045484848 hasLocation W20454848482 @default.
- W2045484848 hasLocation W20454848483 @default.
- W2045484848 hasLocation W20454848484 @default.
- W2045484848 hasOpenAccess W2045484848 @default.
- W2045484848 hasPrimaryLocation W20454848481 @default.
- W2045484848 hasRelatedWork W1966225709 @default.
- W2045484848 hasRelatedWork W2113265247 @default.
- W2045484848 hasRelatedWork W2131249659 @default.
- W2045484848 hasRelatedWork W2559207392 @default.
- W2045484848 hasRelatedWork W2602761843 @default.
- W2045484848 hasRelatedWork W2914484697 @default.
- W2045484848 hasRelatedWork W3215005945 @default.
- W2045484848 hasRelatedWork W4205550511 @default.
- W2045484848 hasRelatedWork W4225904185 @default.
- W2045484848 hasRelatedWork W2096090529 @default.
- W2045484848 hasVolume "55" @default.
- W2045484848 isParatext "false" @default.
- W2045484848 isRetracted "false" @default.
- W2045484848 magId "2045484848" @default.
- W2045484848 workType "article" @default.