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- W2045494920 abstract "Multivariate analyses of 205 positive control experiments in an AmpF ℓSTR© Identifiler© STR kit were used to analyze the factors affecting peak heights at 16 loci. Peak heights were found to be highly correlated between loci and there was evidence for a difference in sensitivity of the two genetic analyzers in the blue channel. Heterozygous balance response at 10 loci was found to behave as a random variable following a beta-distribution with typical median values of 90%, without locus or genetic analyzer effect. Inter-locus balance at 16 loci was influenced by the blue channel effect and a temporal switch of unexplained origin. The implications of these results for the choice of minimum threshold values in quality control are discussed." @default.
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- W2045494920 date "2011-01-01" @default.
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- W2045494920 title "One year variability of peak heights, heterozygous balance and inter-locus balance for the DNA positive control of AmpFSTR© Identifiler© STR kit" @default.
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- W2045494920 doi "https://doi.org/10.1016/j.fsigen.2010.01.020" @default.
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