Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045495424> ?p ?o ?g. }
- W2045495424 endingPage "166" @default.
- W2045495424 startingPage "155" @default.
- W2045495424 abstract "Aneuploidy and chromosome instability are two of the most common abnormalities in cancer cells. They arise through defects in cell division and, specifically, in the unequal segregation of chromosomes between daughter cells during mitosis. A number of cell cycle dependent protein kinases have been identified that control mitotic progression and chromosome segregation. Some of these localize to the centrosome and regulate mitotic spindle formation. One such protein is Nek2, a member of the NIMA-related serine/threonine kinase family. Data are emerging that Nek2 is abnormally expressed in a wide variety of human cancers. In this review, we summarize current knowledge on the expression, regulation and function of Nek2, consider how Nek2 may contribute to chromosome instability, and ask whether it might make an attractive target for chemotherapeutic intervention in human cancer." @default.
- W2045495424 created "2016-06-24" @default.
- W2045495424 creator A5010623455 @default.
- W2045495424 creator A5025469280 @default.
- W2045495424 date "2006-06-01" @default.
- W2045495424 modified "2023-10-14" @default.
- W2045495424 title "Nek2 kinase in chromosome instability and cancer" @default.
- W2045495424 cites W1568426705 @default.
- W2045495424 cites W1835644365 @default.
- W2045495424 cites W1943150066 @default.
- W2045495424 cites W1963786073 @default.
- W2045495424 cites W1967149801 @default.
- W2045495424 cites W1973635610 @default.
- W2045495424 cites W1980577287 @default.
- W2045495424 cites W1984542357 @default.
- W2045495424 cites W1987914156 @default.
- W2045495424 cites W1993860023 @default.
- W2045495424 cites W2002695465 @default.
- W2045495424 cites W2003008967 @default.
- W2045495424 cites W2005204144 @default.
- W2045495424 cites W2009759832 @default.
- W2045495424 cites W2014582878 @default.
- W2045495424 cites W2017513475 @default.
- W2045495424 cites W2021282261 @default.
- W2045495424 cites W2025540821 @default.
- W2045495424 cites W2025829112 @default.
- W2045495424 cites W2027318024 @default.
- W2045495424 cites W2030844064 @default.
- W2045495424 cites W2039439981 @default.
- W2045495424 cites W2041362443 @default.
- W2045495424 cites W2041804034 @default.
- W2045495424 cites W2042889829 @default.
- W2045495424 cites W2043018762 @default.
- W2045495424 cites W2050482803 @default.
- W2045495424 cites W2059780032 @default.
- W2045495424 cites W2060384429 @default.
- W2045495424 cites W2066309710 @default.
- W2045495424 cites W2070484339 @default.
- W2045495424 cites W2076027536 @default.
- W2045495424 cites W2076183717 @default.
- W2045495424 cites W2083753846 @default.
- W2045495424 cites W2085139994 @default.
- W2045495424 cites W2085283608 @default.
- W2045495424 cites W2101453691 @default.
- W2045495424 cites W2102482497 @default.
- W2045495424 cites W2105712639 @default.
- W2045495424 cites W2110541112 @default.
- W2045495424 cites W2123982318 @default.
- W2045495424 cites W2126009415 @default.
- W2045495424 cites W2129798741 @default.
- W2045495424 cites W2130619861 @default.
- W2045495424 cites W2131048186 @default.
- W2045495424 cites W2132786809 @default.
- W2045495424 cites W2138778824 @default.
- W2045495424 cites W2141759890 @default.
- W2045495424 cites W2142451800 @default.
- W2045495424 cites W2148026843 @default.
- W2045495424 cites W2154465929 @default.
- W2045495424 cites W2162681116 @default.
- W2045495424 cites W2167756140 @default.
- W2045495424 cites W2168582232 @default.
- W2045495424 cites W2181582478 @default.
- W2045495424 cites W2189063705 @default.
- W2045495424 cites W2274977411 @default.
- W2045495424 cites W2322865149 @default.
- W2045495424 cites W2740085547 @default.
- W2045495424 doi "https://doi.org/10.1016/j.canlet.2005.06.017" @default.
- W2045495424 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16084011" @default.
- W2045495424 hasPublicationYear "2006" @default.
- W2045495424 type Work @default.
- W2045495424 sameAs 2045495424 @default.
- W2045495424 citedByCount "150" @default.
- W2045495424 countsByYear W20454954242012 @default.
- W2045495424 countsByYear W20454954242013 @default.
- W2045495424 countsByYear W20454954242014 @default.
- W2045495424 countsByYear W20454954242015 @default.
- W2045495424 countsByYear W20454954242016 @default.
- W2045495424 countsByYear W20454954242017 @default.
- W2045495424 countsByYear W20454954242018 @default.
- W2045495424 countsByYear W20454954242019 @default.
- W2045495424 countsByYear W20454954242020 @default.
- W2045495424 countsByYear W20454954242021 @default.
- W2045495424 countsByYear W20454954242022 @default.
- W2045495424 countsByYear W20454954242023 @default.
- W2045495424 crossrefType "journal-article" @default.
- W2045495424 hasAuthorship W2045495424A5010623455 @default.
- W2045495424 hasAuthorship W2045495424A5025469280 @default.
- W2045495424 hasConcept C104317684 @default.
- W2045495424 hasConcept C10447061 @default.
- W2045495424 hasConcept C121608353 @default.
- W2045495424 hasConcept C140752955 @default.
- W2045495424 hasConcept C143425029 @default.
- W2045495424 hasConcept C146276462 @default.
- W2045495424 hasConcept C1491633281 @default.
- W2045495424 hasConcept C175732170 @default.
- W2045495424 hasConcept C178169997 @default.
- W2045495424 hasConcept C2778354886 @default.
- W2045495424 hasConcept C2779672484 @default.