FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045495905> ?p ?o ?g. }

• W2045495905 endingPage "748" @default.
• W2045495905 startingPage "741" @default.
• W2045495905 abstract "Responses of isolated mucosal mast cells (MMC) during infections with either Trichostrongylus colubriformis or Haemonchus contortus were examined by measuring the release of sheep mast cell protease (SMCP) in a degranulation assay. MMC from sheep immune to T. colubriformis released maximal amounts of SMCP and histamine within 0.5h of incubation with larval antigen whereas maximum secretion of leukotrienes occurred 3h after addition of antigen. It was only after 8 weeks of a primary T. colubriformis infection, that MMC released significantly elevated levels of SMCP (23%); this occurred when the worm burden was being rejected. In contrast, the SMCP release from MMC of immune sheep was significantly higher at 40%, and occurred within 1–4 days after challenge (DAC). The SMCP release peaked at 6–8 DAC at 51%, and declined after 56 DAC to <25%. MMC isolated from the duodenum and mid-small intestine of immune sheep released 2–3 times higher proportion of SMCP than did cells recovered from the terminal ileum. Mast cell numbers were similar in the 3 regions but the quantity of globule leucocytes (GL) was 2.5 times higher in the duodenum. During infections with H. contortus in the abomasum, MMC isolated from the small intestine released greater levels of SMCP when incubated with larval antigens than did abomasal MMC. There was no increased release during the first 12 weeks of a primary infection although the SMCP release (23%) from immune MMC at 7–10 DAC was significantly enhanced. Once again the release from MMC isolated from the three intestinal regions of sheep immune to H. contortus was lowest in the terminal ileum. Mast cell numbers were 2 and 3 times higher in the abomasum and duodenum than at the 2 distal sites and a significant number of GL was found only in the abomasum. The results suggest that the sensitization of MMC to parasite antigen during primary infection is closely associated with the development of acquired immunity to either parasite. The response is disseminated throughout the small intestine, and the high levels of SMCP release and number of GL at the site of parasitism probably reflect the greater sensitization of MMC in those region." @default.
• W2045495905 created "2016-06-24" @default.
• W2045495905 creator A5060918501 @default.
• W2045495905 creator A5064750586 @default.
• W2045495905 creator A5084894625 @default.
• W2045495905 date "1995-06-01" @default.
• W2045495905 modified "2023-10-09" @default.
• W2045495905 title "Thesensitization of mucosal mast cells during infections with Trichostrongylus colubriformis or Haemonchus contortus in sheep" @default.
• W2045495905 cites W1949381048 @default.
• W2045495905 cites W1966400525 @default.
• W2045495905 cites W1969067652 @default.
• W2045495905 cites W1972433383 @default.
• W2045495905 cites W1986521790 @default.
• W2045495905 cites W1992381943 @default.
• W2045495905 cites W2000098150 @default.
• W2045495905 cites W2004351423 @default.
• W2045495905 cites W2007991663 @default.
• W2045495905 cites W2014088600 @default.
• W2045495905 cites W2016731316 @default.
• W2045495905 cites W2016932004 @default.
• W2045495905 cites W2024152615 @default.
• W2045495905 cites W2024664301 @default.
• W2045495905 cites W2030527677 @default.
• W2045495905 cites W2038142644 @default.
• W2045495905 cites W2073242557 @default.
• W2045495905 cites W2082424081 @default.
• W2045495905 cites W2086498463 @default.
• W2045495905 cites W2104287859 @default.
• W2045495905 cites W2106914934 @default.
• W2045495905 cites W2115632172 @default.
• W2045495905 cites W2315901679 @default.
• W2045495905 doi "https://doi.org/10.1016/0020-7519(94)00202-y" @default.
• W2045495905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7544771" @default.
• W2045495905 hasPublicationYear "1995" @default.
• W2045495905 type Work @default.
• W2045495905 sameAs 2045495905 @default.
• W2045495905 citedByCount "45" @default.
• W2045495905 countsByYear W20454959052012 @default.
• W2045495905 countsByYear W20454959052013 @default.
• W2045495905 countsByYear W20454959052014 @default.
• W2045495905 countsByYear W20454959052015 @default.
• W2045495905 countsByYear W20454959052016 @default.
• W2045495905 countsByYear W20454959052020 @default.
• W2045495905 countsByYear W20454959052022 @default.
• W2045495905 countsByYear W20454959052023 @default.
• W2045495905 crossrefType "journal-article" @default.
• W2045495905 hasAuthorship W2045495905A5060918501 @default.
• W2045495905 hasAuthorship W2045495905A5064750586 @default.
• W2045495905 hasAuthorship W2045495905A5084894625 @default.
• W2045495905 hasConcept C100544194 @default.
• W2045495905 hasConcept C1122143 @default.
• W2045495905 hasConcept C126322002 @default.
• W2045495905 hasConcept C134018914 @default.
• W2045495905 hasConcept C147483822 @default.
• W2045495905 hasConcept C165901193 @default.
• W2045495905 hasConcept C170493617 @default.
• W2045495905 hasConcept C203014093 @default.
• W2045495905 hasConcept C2775944082 @default.
• W2045495905 hasConcept C2776809568 @default.
• W2045495905 hasConcept C2777226302 @default.
• W2045495905 hasConcept C2777882243 @default.
• W2045495905 hasConcept C2779726688 @default.
• W2045495905 hasConcept C2779825395 @default.
• W2045495905 hasConcept C49802076 @default.
• W2045495905 hasConcept C55493867 @default.
• W2045495905 hasConcept C70262065 @default.
• W2045495905 hasConcept C71924100 @default.
• W2045495905 hasConcept C86803240 @default.
• W2045495905 hasConcept C8891405 @default.
• W2045495905 hasConcept C89423630 @default.
• W2045495905 hasConceptScore W2045495905C100544194 @default.
• W2045495905 hasConceptScore W2045495905C1122143 @default.
• W2045495905 hasConceptScore W2045495905C126322002 @default.
• W2045495905 hasConceptScore W2045495905C134018914 @default.
• W2045495905 hasConceptScore W2045495905C147483822 @default.
• W2045495905 hasConceptScore W2045495905C165901193 @default.
• W2045495905 hasConceptScore W2045495905C170493617 @default.
• W2045495905 hasConceptScore W2045495905C203014093 @default.
• W2045495905 hasConceptScore W2045495905C2775944082 @default.
• W2045495905 hasConceptScore W2045495905C2776809568 @default.
• W2045495905 hasConceptScore W2045495905C2777226302 @default.
• W2045495905 hasConceptScore W2045495905C2777882243 @default.
• W2045495905 hasConceptScore W2045495905C2779726688 @default.
• W2045495905 hasConceptScore W2045495905C2779825395 @default.
• W2045495905 hasConceptScore W2045495905C49802076 @default.
• W2045495905 hasConceptScore W2045495905C55493867 @default.
• W2045495905 hasConceptScore W2045495905C70262065 @default.
• W2045495905 hasConceptScore W2045495905C71924100 @default.
• W2045495905 hasConceptScore W2045495905C86803240 @default.
• W2045495905 hasConceptScore W2045495905C8891405 @default.
• W2045495905 hasConceptScore W2045495905C89423630 @default.
• W2045495905 hasIssue "6" @default.
• W2045495905 hasLocation W20454959051 @default.
• W2045495905 hasLocation W20454959052 @default.
• W2045495905 hasOpenAccess W2045495905 @default.
• W2045495905 hasPrimaryLocation W20454959051 @default.
• W2045495905 hasRelatedWork W1999728735 @default.
• W2045495905 hasRelatedWork W2039586673 @default.

• next