Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045497635> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2045497635 endingPage "96" @default.
- W2045497635 startingPage "87" @default.
- W2045497635 abstract "The apparent heat capacity function measured by high-sensitivity differential scanning calorimetry contains dynamic components of two different origins: (1) an intrinsic component arising from the finite instrument time response; and (2) a sample component arising from the kinetics of the thermal transition under study. The intrinsic instrumental component is always present and its effect on the shape of the experimental curve depends on the magnitude of the calorimeter response time. Usually, high-sensitivity instruments exhibit characteristic time constants varying from 10 to 100 s. This slow response introduces distortions in the shape of the heat capacity function especially at fast scanning rates. In addition to this instrumental component, dynamic effects due to sample relaxation processes also contribute to the shape of the experimental heat capacity profile. Since the nature and magnitude of these effects are a function of the kinetic parameters of the transition, they can be used to obtain kinetic information. This communication presents a dynamic deconvolution technique directed to remove artificial distortions in the shape of the heat capacity function measured at any scanning rate, and to obtain a kinetic characterization of a thermally induced transition. The kinetic characterization obtained by this method allows the researcher to obtain transition relaxation times as a continuous function of temperature. This technique has been applied to the thermal unfolding of ribonuclease A and the pretransition of dipalmitoylphosphatidylcholine (DPPC). In both systems the transition relaxation times are temperature dependent. For the protein system the relaxation time is very slow below the transition temperature (approximately 30 s) and very fast above Tm (less than 1 s) in agreement with direct kinetic measurements. For the pretransition of DPPC, the relaxation time is maximal at the transition midpoint and of the order of approx. 40 s." @default.
- W2045497635 created "2016-06-24" @default.
- W2045497635 creator A5007948012 @default.
- W2045497635 creator A5076837225 @default.
- W2045497635 date "1987-07-01" @default.
- W2045497635 modified "2023-10-01" @default.
- W2045497635 title "Dynamic analysis of differential scanning calorimetry data" @default.
- W2045497635 cites W1967717459 @default.
- W2045497635 cites W1978220465 @default.
- W2045497635 cites W1994760283 @default.
- W2045497635 cites W1996806551 @default.
- W2045497635 cites W2012308391 @default.
- W2045497635 cites W2016924802 @default.
- W2045497635 cites W2018847244 @default.
- W2045497635 cites W2025706122 @default.
- W2045497635 cites W2044110936 @default.
- W2045497635 cites W2062629061 @default.
- W2045497635 cites W2080397024 @default.
- W2045497635 cites W2086446662 @default.
- W2045497635 cites W2093250858 @default.
- W2045497635 cites W2159392498 @default.
- W2045497635 cites W2201892421 @default.
- W2045497635 cites W4300941906 @default.
- W2045497635 doi "https://doi.org/10.1016/0301-4622(87)80049-2" @default.
- W2045497635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3607241" @default.
- W2045497635 hasPublicationYear "1987" @default.
- W2045497635 type Work @default.
- W2045497635 sameAs 2045497635 @default.
- W2045497635 citedByCount "73" @default.
- W2045497635 countsByYear W20454976352012 @default.
- W2045497635 countsByYear W20454976352013 @default.
- W2045497635 countsByYear W20454976352015 @default.
- W2045497635 countsByYear W20454976352016 @default.
- W2045497635 countsByYear W20454976352017 @default.
- W2045497635 countsByYear W20454976352019 @default.
- W2045497635 countsByYear W20454976352021 @default.
- W2045497635 countsByYear W20454976352022 @default.
- W2045497635 countsByYear W20454976352023 @default.
- W2045497635 crossrefType "journal-article" @default.
- W2045497635 hasAuthorship W2045497635A5007948012 @default.
- W2045497635 hasAuthorship W2045497635A5076837225 @default.
- W2045497635 hasConcept C120665830 @default.
- W2045497635 hasConcept C121332964 @default.
- W2045497635 hasConcept C127413603 @default.
- W2045497635 hasConcept C135889238 @default.
- W2045497635 hasConcept C15744967 @default.
- W2045497635 hasConcept C174576160 @default.
- W2045497635 hasConcept C185592680 @default.
- W2045497635 hasConcept C202270520 @default.
- W2045497635 hasConcept C204530211 @default.
- W2045497635 hasConcept C21200559 @default.
- W2045497635 hasConcept C24326235 @default.
- W2045497635 hasConcept C2776029896 @default.
- W2045497635 hasConcept C39519442 @default.
- W2045497635 hasConcept C60205243 @default.
- W2045497635 hasConcept C62520636 @default.
- W2045497635 hasConcept C77805123 @default.
- W2045497635 hasConcept C97355855 @default.
- W2045497635 hasConceptScore W2045497635C120665830 @default.
- W2045497635 hasConceptScore W2045497635C121332964 @default.
- W2045497635 hasConceptScore W2045497635C127413603 @default.
- W2045497635 hasConceptScore W2045497635C135889238 @default.
- W2045497635 hasConceptScore W2045497635C15744967 @default.
- W2045497635 hasConceptScore W2045497635C174576160 @default.
- W2045497635 hasConceptScore W2045497635C185592680 @default.
- W2045497635 hasConceptScore W2045497635C202270520 @default.
- W2045497635 hasConceptScore W2045497635C204530211 @default.
- W2045497635 hasConceptScore W2045497635C21200559 @default.
- W2045497635 hasConceptScore W2045497635C24326235 @default.
- W2045497635 hasConceptScore W2045497635C2776029896 @default.
- W2045497635 hasConceptScore W2045497635C39519442 @default.
- W2045497635 hasConceptScore W2045497635C60205243 @default.
- W2045497635 hasConceptScore W2045497635C62520636 @default.
- W2045497635 hasConceptScore W2045497635C77805123 @default.
- W2045497635 hasConceptScore W2045497635C97355855 @default.
- W2045497635 hasIssue "1" @default.
- W2045497635 hasLocation W20454976351 @default.
- W2045497635 hasLocation W20454976352 @default.
- W2045497635 hasOpenAccess W2045497635 @default.
- W2045497635 hasPrimaryLocation W20454976351 @default.
- W2045497635 hasRelatedWork W1521626205 @default.
- W2045497635 hasRelatedWork W1998195543 @default.
- W2045497635 hasRelatedWork W1998868696 @default.
- W2045497635 hasRelatedWork W2034682024 @default.
- W2045497635 hasRelatedWork W2059853201 @default.
- W2045497635 hasRelatedWork W2136851655 @default.
- W2045497635 hasRelatedWork W2371946129 @default.
- W2045497635 hasRelatedWork W2519451927 @default.
- W2045497635 hasRelatedWork W2616851429 @default.
- W2045497635 hasRelatedWork W3132805086 @default.
- W2045497635 hasVolume "27" @default.
- W2045497635 isParatext "false" @default.
- W2045497635 isRetracted "false" @default.
- W2045497635 magId "2045497635" @default.
- W2045497635 workType "article" @default.