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- W2045550107 abstract "Significance Recent reports suggest that antiretroviral therapy (ART) initiated early after HIV infection increases the likelihood of post-treatment control (PTC) in which plasma virus remains undetectable after treatment cessation. However, only a small fraction of patients treated early attain PTC. We develop a mathematical model of HIV infection that provides insight into these phenomena, suggesting that treatments restricting or reducing the latent reservoir size may allow immune responses to control infection posttreatment. Our model makes predictions about immune response strengths and latent reservoir sizes needed for a patient taken off treatment to exhibit PTC that may help guide future studies." @default.
- W2045550107 created "2016-06-24" @default.
- W2045550107 creator A5011620477 @default.
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- W2045550107 date "2015-04-13" @default.
- W2045550107 modified "2023-10-12" @default.
- W2045550107 title "Post-treatment control of HIV infection" @default.
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- W2045550107 doi "https://doi.org/10.1073/pnas.1419162112" @default.
- W2045550107 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4418889" @default.
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