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- W2045558214 abstract "Introduction Abnormalities of serum sodium levels and salt excretion in patients with cerebral disease have attracted considerable attention in recent years.1-7Persistent, excessive sodium loss in the urine with hyponatremia and even circulatory collapse is a rare syndrome which has been described in detail.6Hypernatremia is much more common, may be complicated by azotemia, and occurs with particular frequency in patients with damage to the frontal lobes and/or hypothalamus.1,7It has been postulated that these latter cases are due to chronic dehydration, related in all probability to dulling of the sensation of thirst, with or without an associated diabetes insipidus.8-10However, such an explanation has not found universal acceptance. In experimental animals, Lewy and Gassman11found hyperchloremia and hypochloruria following passage of coagulating currents into the paroptic region of the hypothalamus, while Keeler12observed sodium diuresis in the first 24 hours after paraventricular lesions." @default.
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- W2045558214 date "1961-02-01" @default.
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- W2045558214 title "Diencephalic and Frontal Lobe Lesions" @default.
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- W2045558214 doi "https://doi.org/10.1001/archneur.1961.00450080064007" @default.
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