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- W2045561908 abstract "The cannabinoid system is now recognized as a regulator of both the nervous and immune systems. Although marijuana has been used for centuries for the treatment of a variety of disorders, its therapeutic mechanisms are only now being understood. The best‐studied plant cannabinoid, Δ 9 ‐tetrahydrocannabinol (THC), produced by Cannabis sativa and found in marijuana, has shown evidence of being immunosuppressive in both in vivo and in vitro . Since THC binds to at least two receptors that are differentially expressed by the immune and nervous systems, it has not been possible to clearly discriminate the biological effects it exerts in the two systems. In addition, endogenous cannabinoids have also been described that bind to both receptors and exert both neuronal and immune modulatory activity. The generation of mice deficient in specific cannabinoid receptors has facilitated studies to discriminate cannabinoid‐specific functions. This review focuses on the function of the cannabinoid receptor 2 (CB 2 ), primarily expressed in the immune system, in regulating T cell effector functions associated with autoimmune inflammation in the central nervous system (CNS). British Journal of Pharmacology (2008) 153 , 271–276; doi: 10.1038/sj.bjp.0707493 ; published online 8 October 2007" @default.
- W2045561908 created "2016-06-24" @default.
- W2045561908 creator A5081297354 @default.
- W2045561908 date "2008-01-01" @default.
- W2045561908 modified "2023-09-25" @default.
- W2045561908 title "Direct suppression of autoreactive lymphocytes in the central nervous system via the CB<sub>2</sub>receptor" @default.
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- W2045561908 cites W1606443939 @default.
- W2045561908 cites W1938701383 @default.
- W2045561908 cites W1956139961 @default.
- W2045561908 cites W1971943746 @default.
- W2045561908 cites W1972403397 @default.
- W2045561908 cites W1974642601 @default.
- W2045561908 cites W1978007980 @default.
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- W2045561908 cites W2022684622 @default.
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- W2045561908 cites W2023430340 @default.
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- W2045561908 doi "https://doi.org/10.1038/sj.bjp.0707493" @default.
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