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- W2045571006 abstract "The mottled (Mo) mouse is an animal model of the human congenital copper (Cu) deficiency disorder, Menkes' kinky hair syndrome. Intraperitoneal Cu chloride injections have been shown to produce clinical and morphological improvements in this mutant mouse. Cu injections (10 micrograms/g) on postnatal days 7 and 10 are shown to increase endogenous activity of the Cu-dependent enzyme dopamine-beta-hydroxylase in the brains of Mo mice. The present study provides insight into the long-term neurochemical changes resulting from a possible treatment regimen for Menkes' kinky hair syndrome." @default.
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- W2045571006 date "1983-12-01" @default.
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- W2045571006 title "Congenital Copper Deficiency: Copper Therapy and Dopamine-?-Hydroxylase Activity in the Mottled (Brindled) Mouse" @default.
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- W2045571006 doi "https://doi.org/10.1111/j.1471-4159.1983.tb00876.x" @default.
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