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- W2045582512 abstract "Animals infected with a strain of Pseudomonas aeruginosa were found to be depleted of blood glucose and liver glycogen. The kinetics of the disappearance of injected nonradioactive glucose and tracer U-14C-glucose were studied together with the kinetics of the appearance of 14C in the animal's glucose space after injection of 2-14C-pyruvic acid. A four-compartment cyclic model, analogous to the Cori cycle, was used to analyze the data. Rates of transfer of metabolites were examined with the aid of an analog computer. The results suggest that the infected animals do not synthesize glucose from glycolytic pathway precursors at a normal rate. The computer technique permits estimation of proportional least squares error in the course of curve fitting. It appears to have considerable general utility." @default.
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- W2045582512 date "1968-08-01" @default.
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- W2045582512 title "Carbohydrate metabolism in pseudomonas infection" @default.
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- W2045582512 doi "https://doi.org/10.1016/0010-4809(68)90008-6" @default.
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