FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045584911> ?p ?o ?g. }

• W2045584911 endingPage "898" @default.
• W2045584911 startingPage "892" @default.
• W2045584911 abstract "ALKBH5, a member of AlkB family proteins, has been reported as a mammalian N(6)-methyladenosine (m(6)A) RNA demethylase. Here we report the crystal structure of zebrafish ALKBH5 (fALKBH5) with the resolution of 1.65Å. Structural superimposition shows that fALKBH5 is comprised of a conserved jelly-roll motif. However, it possesses a loop that interferes potential binding of a duplex nucleic acid substrate, suggesting an important role in substrate selection. In addition, several active site residues are different between the two known m(6)A RNA demethylases, ALKBH5 and FTO, which may result in their slightly different pathways of m(6)A demethylation." @default.
• W2045584911 created "2016-06-24" @default.
• W2045584911 creator A5014005102 @default.
• W2045584911 creator A5022499603 @default.
• W2045584911 creator A5025013285 @default.
• W2045584911 creator A5039072550 @default.
• W2045584911 creator A5046956714 @default.
• W2045584911 creator A5052855859 @default.
• W2045584911 creator A5075497795 @default.
• W2045584911 creator A5091114864 @default.
• W2045584911 date "2014-02-20" @default.
• W2045584911 modified "2023-10-02" @default.
• W2045584911 title "Crystal structure of the RNA demethylase ALKBH5 from zebrafish" @default.
• W2045584911 cites W1924636346 @default.
• W2045584911 cites W1967700647 @default.
• W2045584911 cites W1972021276 @default.
• W2045584911 cites W1977049730 @default.
• W2045584911 cites W1983255679 @default.
• W2045584911 cites W1984516599 @default.
• W2045584911 cites W1985944976 @default.
• W2045584911 cites W2011400542 @default.
• W2045584911 cites W2017991488 @default.
• W2045584911 cites W2025980739 @default.
• W2045584911 cites W2028335133 @default.
• W2045584911 cites W2042765650 @default.
• W2045584911 cites W2065847836 @default.
• W2045584911 cites W2068198916 @default.
• W2045584911 cites W2071930821 @default.
• W2045584911 cites W2078964320 @default.
• W2045584911 cites W2083772202 @default.
• W2045584911 cites W2084588717 @default.
• W2045584911 cites W2093764457 @default.
• W2045584911 cites W2097660065 @default.
• W2045584911 cites W2110102140 @default.
• W2045584911 cites W2110678911 @default.
• W2045584911 cites W2122609893 @default.
• W2045584911 cites W2122767064 @default.
• W2045584911 cites W2127039851 @default.
• W2045584911 cites W2129397714 @default.
• W2045584911 cites W2138871437 @default.
• W2045584911 cites W2142427369 @default.
• W2045584911 cites W2157382511 @default.
• W2045584911 cites W2165547003 @default.
• W2045584911 cites W2169494000 @default.
• W2045584911 cites W2487944395 @default.
• W2045584911 doi "https://doi.org/10.1016/j.febslet.2014.02.021" @default.
• W2045584911 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3982313" @default.
• W2045584911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24561204" @default.
• W2045584911 hasPublicationYear "2014" @default.
• W2045584911 type Work @default.
• W2045584911 sameAs 2045584911 @default.
• W2045584911 citedByCount "50" @default.
• W2045584911 countsByYear W20455849112014 @default.
• W2045584911 countsByYear W20455849112015 @default.
• W2045584911 countsByYear W20455849112016 @default.
• W2045584911 countsByYear W20455849112017 @default.
• W2045584911 countsByYear W20455849112018 @default.
• W2045584911 countsByYear W20455849112019 @default.
• W2045584911 countsByYear W20455849112020 @default.
• W2045584911 countsByYear W20455849112021 @default.
• W2045584911 countsByYear W20455849112022 @default.
• W2045584911 countsByYear W20455849112023 @default.
• W2045584911 crossrefType "journal-article" @default.
• W2045584911 hasAuthorship W2045584911A5014005102 @default.
• W2045584911 hasAuthorship W2045584911A5022499603 @default.
• W2045584911 hasAuthorship W2045584911A5025013285 @default.
• W2045584911 hasAuthorship W2045584911A5039072550 @default.
• W2045584911 hasAuthorship W2045584911A5046956714 @default.
• W2045584911 hasAuthorship W2045584911A5052855859 @default.
• W2045584911 hasAuthorship W2045584911A5075497795 @default.
• W2045584911 hasAuthorship W2045584911A5091114864 @default.
• W2045584911 hasBestOaLocation W20455849112 @default.
• W2045584911 hasConcept C104317684 @default.
• W2045584911 hasConcept C134935766 @default.
• W2045584911 hasConcept C150194340 @default.
• W2045584911 hasConcept C153911025 @default.
• W2045584911 hasConcept C185592680 @default.
• W2045584911 hasConcept C190727270 @default.
• W2045584911 hasConcept C202199734 @default.
• W2045584911 hasConcept C24107716 @default.
• W2045584911 hasConcept C2775963939 @default.
• W2045584911 hasConcept C2776878037 @default.
• W2045584911 hasConcept C2777721518 @default.
• W2045584911 hasConcept C2781364455 @default.
• W2045584911 hasConcept C33288867 @default.
• W2045584911 hasConcept C552990157 @default.
• W2045584911 hasConcept C55493867 @default.
• W2045584911 hasConcept C64927066 @default.
• W2045584911 hasConcept C67705224 @default.
• W2045584911 hasConcept C86803240 @default.
• W2045584911 hasConcept C91965660 @default.
• W2045584911 hasConcept C95444343 @default.
• W2045584911 hasConceptScore W2045584911C104317684 @default.
• W2045584911 hasConceptScore W2045584911C134935766 @default.
• W2045584911 hasConceptScore W2045584911C150194340 @default.
• W2045584911 hasConceptScore W2045584911C153911025 @default.
• W2045584911 hasConceptScore W2045584911C185592680 @default.
• W2045584911 hasConceptScore W2045584911C190727270 @default.

• next