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- W2045588751 endingPage "e22943" @default.
- W2045588751 startingPage "e22943" @default.
- W2045588751 abstract "Accumulating evidence supports the role of leukemic stem cells (LSCs) in the high relapse rate of acute myeloid leukemia (AML) patients. The clinical relevance of LSCs, which were originally characterized in xenograft models, has recently been confirmed by the finding that stem cell-like gene expression signatures can predict the clinical outcome of AML patients. The targeted elimination of LSCs might hence constitute an efficient therapeutic approach to AML. Here, we review immunotherapeutic strategies that target LSC-associated antigens, including T cell-mediated and monoclonal antibody-based regimens. Attention is given to the issue of antigen specificity because this is relevant to the therapeutic window and determines the superiority of LSC-targeting immunotherapy." @default.
- W2045588751 created "2016-06-24" @default.
- W2045588751 creator A5001976368 @default.
- W2045588751 creator A5048593632 @default.
- W2045588751 creator A5082232325 @default.
- W2045588751 date "2013-02-01" @default.
- W2045588751 modified "2023-10-05" @default.
- W2045588751 title "Can immunotherapy specifically target acute myeloid leukemic stem cells?" @default.
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- W2045588751 cites W1756759934 @default.
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- W2045588751 cites W1966371404 @default.
- W2045588751 cites W1967358345 @default.
- W2045588751 cites W1975427849 @default.
- W2045588751 cites W1975585650 @default.
- W2045588751 cites W1975736583 @default.
- W2045588751 cites W1975889870 @default.
- W2045588751 cites W1979421565 @default.
- W2045588751 cites W1983641075 @default.
- W2045588751 cites W1986766697 @default.
- W2045588751 cites W1988397531 @default.
- W2045588751 cites W1992343552 @default.
- W2045588751 cites W1993423043 @default.
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- W2045588751 cites W1998321969 @default.
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- W2045588751 cites W2016289354 @default.
- W2045588751 cites W2021437613 @default.
- W2045588751 cites W2024763401 @default.
- W2045588751 cites W2026566525 @default.
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- W2045588751 cites W2070387456 @default.
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- W2045588751 doi "https://doi.org/10.4161/onci.22943" @default.
- W2045588751 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3601163" @default.
- W2045588751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23526057" @default.
- W2045588751 hasPublicationYear "2013" @default.
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