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• W2045594625 startingPage "12745" @default.
• W2045594625 abstract "Pax-3 is a member of the Pax family of transcription factors involved in transcriptional control events during embryonic development. Here we report a functional dissection of the Pax-3 protein and describe the protein domains which are responsible for different activities. A transcription inhibition activity is located in the first 90 N-terminal amino acids and includes part of the paired domain. Furthermore, the C terminus of Pax-3 is able to confer transcriptional activation of basal promoters. Pax-3 can utilize both transcription modulating functions and activates transcription over a narrow range of protein concentration in the presence of promoter elements containing functional binding sites." @default.
• W2045594625 created "2016-06-24" @default.
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• W2045594625 date "1994-12-20" @default.
• W2045594625 modified "2023-10-18" @default.
• W2045594625 title "Pax-3 contains domains for transcription activation and transcription inhibition." @default.
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• W2045594625 doi "https://doi.org/10.1073/pnas.91.26.12745" @default.
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