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- W2045596587 abstract "Abstract The existence of two (generally different) binding sites per protomer for the same ligand has already been observed (“double-site enzymes”). Furthermore, in some instances, the two sites appear to be shared in common by two or more ligands (“squatting”). The theoretical implications of such cases have been emphasized here using a generalization of an allosteric V model. This model, by taking into account the competition between ligands which occurs in vivo, evidences various, or even peculiar regulatory patterns, and could be of general physiological interest. It has been illustrated here by some real systems." @default.
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- W2045596587 date "1977-10-01" @default.
- W2045596587 modified "2023-10-18" @default.
- W2045596587 title "Double-site enzymes and squatting A study of the regulation by one or several ligands binding at two different classes of site" @default.
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- W2045596587 doi "https://doi.org/10.1016/0022-5193(77)90066-2" @default.
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