Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045604864> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2045604864 endingPage "1322" @default.
- W2045604864 startingPage "1318" @default.
- W2045604864 abstract "The pathophysiologic events that lead to the loss of airway compensation in obstructive sleep apnea (OSA) are poorly understood. The development of airway instability may be secondary to changes in neurologic control, airway morphology, or both. To identify potential histopathologic features of pharyngeal tissues that may contribute to OSA, transverse sections of the distal soft palate and uvula were qualitatively compared using light and electron microscopy from 4 severe apneics (>50 apnea/hour), 4 severe snorers (<20 apnea/hour), and 4 nonsnorers. Light microscopy of both apneics and snorers revealed mucous gland hypertrophy with ductal dilation and focal squamous metaplasia, disruption of muscle bundles by infiltrating mucous glands, focal atrophy of muscle fibers, and extensive edema of the lamina propria with vascular dilation. Severe snorers did not differ qualitatively from apneics in the characteristic changes found; however, some snorers had less extensive changes. No distinctive histopathologic findings could be associated with the development of apnea. Electron microscopy of severe apneics identified frequent focal degeneration of myelinated nerve fibers and axons. The finding of similar histopathologic changes in apneics and severe snorers supports previous speculation of a common etiology not directly related to apnea, such as vibratory trauma to pharyngeal tissues. Degenerative changes in peripheral nerves, identified on electron microscopy, however, may contribute to airway instability and the development of obstructive apnea by impairing pharyngeal reflexes." @default.
- W2045604864 created "2016-06-24" @default.
- W2045604864 creator A5010507630 @default.
- W2045604864 creator A5069243227 @default.
- W2045604864 creator A5074541473 @default.
- W2045604864 date "1991-12-01" @default.
- W2045604864 modified "2023-09-27" @default.
- W2045604864 title "Histopathologic changes in snoring and obstructive sleep apnea syndrome" @default.
- W2045604864 cites W1891670235 @default.
- W2045604864 cites W1993568235 @default.
- W2045604864 cites W2006701755 @default.
- W2045604864 cites W2017356201 @default.
- W2045604864 cites W2022952939 @default.
- W2045604864 cites W2033290383 @default.
- W2045604864 cites W2045388471 @default.
- W2045604864 cites W2154407061 @default.
- W2045604864 cites W2414126802 @default.
- W2045604864 doi "https://doi.org/10.1002/lary.5541011211" @default.
- W2045604864 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1766303" @default.
- W2045604864 hasPublicationYear "1991" @default.
- W2045604864 type Work @default.
- W2045604864 sameAs 2045604864 @default.
- W2045604864 citedByCount "178" @default.
- W2045604864 countsByYear W20456048642012 @default.
- W2045604864 countsByYear W20456048642013 @default.
- W2045604864 countsByYear W20456048642014 @default.
- W2045604864 countsByYear W20456048642015 @default.
- W2045604864 countsByYear W20456048642016 @default.
- W2045604864 countsByYear W20456048642017 @default.
- W2045604864 countsByYear W20456048642018 @default.
- W2045604864 countsByYear W20456048642019 @default.
- W2045604864 countsByYear W20456048642020 @default.
- W2045604864 countsByYear W20456048642021 @default.
- W2045604864 countsByYear W20456048642022 @default.
- W2045604864 countsByYear W20456048642023 @default.
- W2045604864 crossrefType "journal-article" @default.
- W2045604864 hasAuthorship W2045604864A5010507630 @default.
- W2045604864 hasAuthorship W2045604864A5069243227 @default.
- W2045604864 hasAuthorship W2045604864A5074541473 @default.
- W2045604864 hasConcept C105702510 @default.
- W2045604864 hasConcept C105922876 @default.
- W2045604864 hasConcept C126322002 @default.
- W2045604864 hasConcept C142724271 @default.
- W2045604864 hasConcept C2776006263 @default.
- W2045604864 hasConcept C2781326671 @default.
- W2045604864 hasConcept C42219234 @default.
- W2045604864 hasConcept C71924100 @default.
- W2045604864 hasConceptScore W2045604864C105702510 @default.
- W2045604864 hasConceptScore W2045604864C105922876 @default.
- W2045604864 hasConceptScore W2045604864C126322002 @default.
- W2045604864 hasConceptScore W2045604864C142724271 @default.
- W2045604864 hasConceptScore W2045604864C2776006263 @default.
- W2045604864 hasConceptScore W2045604864C2781326671 @default.
- W2045604864 hasConceptScore W2045604864C42219234 @default.
- W2045604864 hasConceptScore W2045604864C71924100 @default.
- W2045604864 hasIssue "12" @default.
- W2045604864 hasLocation W20456048641 @default.
- W2045604864 hasLocation W20456048642 @default.
- W2045604864 hasOpenAccess W2045604864 @default.
- W2045604864 hasPrimaryLocation W20456048641 @default.
- W2045604864 hasRelatedWork W2077056429 @default.
- W2045604864 hasRelatedWork W2140876245 @default.
- W2045604864 hasRelatedWork W2319407515 @default.
- W2045604864 hasRelatedWork W2390361370 @default.
- W2045604864 hasRelatedWork W2403480355 @default.
- W2045604864 hasRelatedWork W2413082403 @default.
- W2045604864 hasRelatedWork W2796438762 @default.
- W2045604864 hasRelatedWork W4249989462 @default.
- W2045604864 hasRelatedWork W4295775062 @default.
- W2045604864 hasRelatedWork W4311173377 @default.
- W2045604864 hasVolume "101" @default.
- W2045604864 isParatext "false" @default.
- W2045604864 isRetracted "false" @default.
- W2045604864 magId "2045604864" @default.
- W2045604864 workType "article" @default.