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- W2045608210 abstract "The in vivo toxicity and sublethal biochemical effects of chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile) were evaluated in the channel catfish (lctalurus punctatus). The static 96hr LC50 value for chlorothalonil was 52 μg/L, indicating that chlorothalonil is highly acutely toxic to channel catfish. Sublethal chlorothalonil exposure for 6 days resulted in acute necrosis of the intestinal epithelial lining in 57% of the treated catfish. However, no treatment-related pathological lesions were observed in liver, gills, posterior kidney, brain, spleen, or heart. Catfish exposed to 13 μg/L chlorothalonil for 72 hr had increased tissue glutathione (GSH) concentrations in liver, posterior kidney and gills, suggesting a protective role of tissue GSH towards chlorothalonil exposure." @default.
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- W2045608210 date "1992-01-01" @default.
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- W2045608210 title "The acute toxicity and sublethal effects of chlorothalonil in channel catfish (Ictalurus punctatus)" @default.
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- W2045608210 doi "https://doi.org/10.1016/0045-6535(92)90561-5" @default.
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