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- W2045624537 abstract "Pyrazole-based β-aminonitriles and β-amino-carbaldehydes as bifunctional building blocks are introduced in a facile copper(II)-catalysed one-pot domino generation of multiple N-containing heterobi- and tricycles. This streamlined synthetic approach permits easy access to novel pyrazole-fused imidazo- and pyrimido[1,2-c]pyrimidinones and to pyrazolo[3,4-d]pyrimidinone species with isolated yields up to 90%. The present study also reveals a unique amine–isocyanate coupling promotion via copper(II)-based catalytic activation." @default.
- W2045624537 created "2016-06-24" @default.
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- W2045624537 date "2013-01-01" @default.
- W2045624537 modified "2023-10-09" @default.
- W2045624537 title "Synthesis of novel pyrazole-based heterocycles via a copper(ii)-catalysed domino annulation" @default.
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- W2045624537 doi "https://doi.org/10.1039/c3ob41146j" @default.
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