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• W2045637649 abstract "Objective:Hyperkalaemia is a potentially lethal electrolyte disorder. The objective of this study was to determine if the causes of hyperkalaemia-related visits to the emergency department (ED) have changed since 25 years.Methods:All patients presenting to the ED with hyperkalaemia between January 2009 and August 2011 were included in this retrospective, single-centre study. Patients were divided into one of these three categories: mild (5·2⩽K+<5·8 mEq/l), moderate (5·8⩽K+<7·0 mEq/l) or severe hyperkalaemia (K+⩾7·0 mEq/l). The causes of hyperkalaemia were divided into three groups: renal failure (RF), potassium-increasing drugs (PIDs) or others.Results:Overall, 139 patients with hyperkalaemia were included in the study (mean K+ of 6·2 mEq/l): 35% with mild, 49% with moderate and 16% with severe hyperkalaemia. Eighty-three per cent of patients (n = 115) had RF with creatinine levels ⩾1·25 mg/dl or estimated glomerular filtration rate (eGFR) levels ⩽60 ml/min/1·73 m2. Serum potassium levels were significantly related with creatinine and eGFR values (P<0·001). The severity of hyperkalaemia was significantly related with creatinine levels ⩾1·25 mg/dl (P = 0·002) and eGFR values ⩽60 ml/min/1·73 m2 (P = 0·005). Seventy-five per cent of patients (n = 105) were taking PIDs. Potassium levels were significantly related with PIDs (P<0·001), in particularly spironolactone (P = 0·001) and angiotensin-converting enzyme inhibitors (P = 0·008). The category ‘others’ included 7% of patients (n = 10).Conclusions:RF (83%) and PIDs (75%) remain common causes of hyperkalaemia. Hyperkalaemia is significantly related with four variables: creatinine levels, spironolactone, ACEIs and beta-blocker intake. The causes of hyperkalaemia have not changed in recent years." @default.
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• W2045637649 date "2014-06-18" @default.
• W2045637649 modified "2023-09-26" @default.
• W2045637649 title "A determination of the current causes of hyperkalaemia and whether they have changed over the past 25 years" @default.
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• W2045637649 doi "https://doi.org/10.1179/0001551214z.00000000077" @default.
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