FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045641942> ?p ?o ?g. }

• W2045641942 endingPage "750" @default.
• W2045641942 startingPage "737" @default.
• W2045641942 abstract "• Responses elicited by dlPAG activation require the neuronal activity in the BLA. • Responses caused by the dlPAG activation depend on glutamatergic activity of BLA. • The same role was not observed for the central amygdala. There is ample evidence that both lateral/dorsolateral periaqueductal gray (l/dlPAG) and basolateral amygdala (BLA) are essential for the regulation of the autonomic responses evoked during innate reactions to threatening stimuli. However, it is not well established to what extent the BLA regulates the upstream functional connection from the l/dlPAG. Here we evaluated the role of the BLA and its glutamatergic receptors in the cardiovascular responses induced by l/dlPAG stimulation in rats. We examined the influence of acute inhibition of the BLA, unilaterally, by injecting muscimol on the cardiovascular responses evoked by the injection of N-methyl D-aspartate (NMDA) into the l/dlPAG. We also evaluated the role of BLA ionotropic glutamate receptors in these responses by injecting antagonists of NMDA and AMPA/kainate receptor subtypes into the BLA. Our results show that the microinjection of NMDA in the BLA increased the mean arterial pressure (MAP) and heart rate (HR). Injection of NMDA into the l/dlPAG caused similar increases in these variables, which was prevented by the prior injection of muscimol, a GABA A agonist, into the BLA. Moreover, injection of glutamatergic antagonists (2-amino-5-phosphonopentanoate (AP5) and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQ X )) into the BLA reduced the increase in MAP and HR induced by l/dlPAG activation. Finally, the inhibition of the central amygdala neurons failed to reduce the cardiovascular changes induced by l/dlPAG activation. These results indicate that physiological responses elicited by l/dlPAG activation require the neuronal activity in the BLA. This ascending excitatory pathway from the l/dlPAG to the BLA might ensure the expression of the autonomic component of the defense reaction." @default.
• W2045641942 created "2016-06-24" @default.
• W2045641942 creator A5011248238 @default.
• W2045641942 creator A5027010379 @default.
• W2045641942 creator A5050694650 @default.
• W2045641942 creator A5055074304 @default.
• W2045641942 creator A5060443343 @default.
• W2045641942 creator A5077206486 @default.
• W2045641942 date "2015-01-01" @default.
• W2045641942 modified "2023-09-26" @default.
• W2045641942 title "Amygdalar neuronal activity mediates the cardiovascular responses evoked from the dorsolateral periaqueductal gray in conscious rats" @default.
• W2045641942 cites W142616790 @default.
• W2045641942 cites W1514119082 @default.
• W2045641942 cites W1659220516 @default.
• W2045641942 cites W1801330609 @default.
• W2045641942 cites W1941211934 @default.
• W2045641942 cites W1964250712 @default.
• W2045641942 cites W1965529792 @default.
• W2045641942 cites W1966588946 @default.
• W2045641942 cites W1967318820 @default.
• W2045641942 cites W1972685191 @default.
• W2045641942 cites W1977464083 @default.
• W2045641942 cites W1980473712 @default.
• W2045641942 cites W1980741065 @default.
• W2045641942 cites W1985871295 @default.
• W2045641942 cites W1991471889 @default.
• W2045641942 cites W1991971563 @default.
• W2045641942 cites W1997065612 @default.
• W2045641942 cites W2001190007 @default.
• W2045641942 cites W2002583606 @default.
• W2045641942 cites W2004928159 @default.
• W2045641942 cites W2009482341 @default.
• W2045641942 cites W2009587030 @default.
• W2045641942 cites W2010685038 @default.
• W2045641942 cites W2012940067 @default.
• W2045641942 cites W2014168974 @default.
• W2045641942 cites W2017861638 @default.
• W2045641942 cites W2035433051 @default.
• W2045641942 cites W2040527392 @default.
• W2045641942 cites W2041504419 @default.
• W2045641942 cites W2043624001 @default.
• W2045641942 cites W2054892340 @default.
• W2045641942 cites W2057317784 @default.
• W2045641942 cites W2079964665 @default.
• W2045641942 cites W2080397713 @default.
• W2045641942 cites W2082624134 @default.
• W2045641942 cites W2087319022 @default.
• W2045641942 cites W2091698136 @default.
• W2045641942 cites W2102384381 @default.
• W2045641942 cites W2108845151 @default.
• W2045641942 cites W2111083088 @default.
• W2045641942 cites W2111637761 @default.
• W2045641942 cites W2122660499 @default.
• W2045641942 cites W2135964605 @default.
• W2045641942 cites W2142259845 @default.
• W2045641942 cites W2143184913 @default.
• W2045641942 cites W2147780562 @default.
• W2045641942 cites W2163815564 @default.
• W2045641942 cites W272796045 @default.
• W2045641942 doi "https://doi.org/10.1016/j.neuroscience.2014.10.055" @default.
• W2045641942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25451289" @default.
• W2045641942 hasPublicationYear "2015" @default.
• W2045641942 type Work @default.
• W2045641942 sameAs 2045641942 @default.
• W2045641942 citedByCount "9" @default.
• W2045641942 countsByYear W20456419422015 @default.
• W2045641942 countsByYear W20456419422016 @default.
• W2045641942 countsByYear W20456419422017 @default.
• W2045641942 countsByYear W20456419422018 @default.
• W2045641942 countsByYear W20456419422019 @default.
• W2045641942 countsByYear W20456419422020 @default.
• W2045641942 crossrefType "journal-article" @default.
• W2045641942 hasAuthorship W2045641942A5011248238 @default.
• W2045641942 hasAuthorship W2045641942A5027010379 @default.
• W2045641942 hasAuthorship W2045641942A5050694650 @default.
• W2045641942 hasAuthorship W2045641942A5055074304 @default.
• W2045641942 hasAuthorship W2045641942A5060443343 @default.
• W2045641942 hasAuthorship W2045641942A5077206486 @default.
• W2045641942 hasBestOaLocation W20456419422 @default.
• W2045641942 hasConcept C126322002 @default.
• W2045641942 hasConcept C15744967 @default.
• W2045641942 hasConcept C160268369 @default.
• W2045641942 hasConcept C169760540 @default.
• W2045641942 hasConcept C170493617 @default.
• W2045641942 hasConcept C189184402 @default.
• W2045641942 hasConcept C2778938600 @default.
• W2045641942 hasConcept C2779144063 @default.
• W2045641942 hasConcept C2779188335 @default.
• W2045641942 hasConcept C2780451725 @default.
• W2045641942 hasConcept C2780648746 @default.
• W2045641942 hasConcept C2781069035 @default.
• W2045641942 hasConcept C529278444 @default.
• W2045641942 hasConcept C552161191 @default.
• W2045641942 hasConcept C61174792 @default.
• W2045641942 hasConcept C67018056 @default.
• W2045641942 hasConcept C71924100 @default.
• W2045641942 hasConceptScore W2045641942C126322002 @default.
• W2045641942 hasConceptScore W2045641942C15744967 @default.

• next