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- W2045643757 abstract "An immediate cellular response to DNA damage is the synthesis of poly(ADP-ribose) by the enzyme poly(ADP-ribose) polymerase (PARP). This nuclear enzyme and the unique post-translational modification it catalyzes have long been considered to function exclusively in cellular surveillance of genotoxic stress. The recent identification of multiple members of a PARP family might force a revision of this concept. The novel primary structures and subcellular localizations for some of these PARPs suggests new and unexpected roles for poly(ADP-ribosyl)ation in telomere replication and cellular transport." @default.
- W2045643757 created "2016-06-24" @default.
- W2045643757 creator A5057667371 @default.
- W2045643757 date "2001-03-01" @default.
- W2045643757 modified "2023-10-13" @default.
- W2045643757 title "The world according to PARP" @default.
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- W2045643757 doi "https://doi.org/10.1016/s0968-0004(00)01780-1" @default.
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