FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045702804> ?p ?o ?g. }

• W2045702804 abstract "The aim of this study was to evaluate the feasibility of induction docetaxel, cisplatin, and 5-fluorouracil chemotherapy followed by concurrent weekly cisplatin chemoradiotherapy for patients with locally advanced head and neck squamous cell carcinoma (HNSCC).Between 2010 and 2013, 30 patients with Stage IV HNSCC were treated in Hokkaido University Hospital with three cycles of induction chemotherapy (docetaxel 75 mg/m(2) and cisplatin 75 mg/m(2), day 1; and 5-fluorouracil 750 mg/m(2)/day 120 h continuous infusion, every 3 weeks) followed by concurrent weekly cisplatin (40 mg/m(2), on weeks 1, 2, 3, 5, 6 and 7) chemoradiotherapy.Three courses of induction chemotherapy were performed in 25 patients (83%) with grade 3-4 toxicities during induction chemotherapy observed in 22 patients (73%). The major toxicities were hematologic, with 22 cases (73%) showing grade 3-4 neutropenia. Radiotherapy was completed (70 Gy) in 29 patients (97%), while a total of 19 patients (63%) completed five (13 patients) or six (6 patients) courses of chemotherapy. During concurrent chemoradiotherapy, no grade 4 hematological toxicities were observed. Grade 4 dermatitis was observed in one patient, and grade 3 mucositis was observed in 12 patients. There were no treatment-related deaths during the induction chemotherapy or concurrent chemoradiotherapy. The 1- and 2-year progression-free survival rates and the 1- and 2-year overall survival rates were 86%, 72%, and 89%, 81%, respectively.Sequential therapy composed of induction chemotherapy followed by concurrent weekly cisplatin chemoradiotherapy is feasible, showing encouraging results in patients with locally advanced HNSCC. Concurrent weekly cisplatin chemoradiotherapy following induction chemotherapy appears to be a suitable alternative to three-weekly high-dose cisplatin therapy." @default.
• W2045702804 created "2016-06-24" @default.
• W2045702804 creator A5005371127 @default.
• W2045702804 creator A5020774876 @default.
• W2045702804 creator A5026356023 @default.
• W2045702804 creator A5027961713 @default.
• W2045702804 creator A5028998584 @default.
• W2045702804 creator A5037474733 @default.
• W2045702804 creator A5045166286 @default.
• W2045702804 creator A5045604410 @default.
• W2045702804 creator A5052320966 @default.
• W2045702804 creator A5054540480 @default.
• W2045702804 creator A5055606224 @default.
• W2045702804 creator A5061496996 @default.
• W2045702804 creator A5066514747 @default.
• W2045702804 creator A5072144503 @default.
• W2045702804 creator A5088707584 @default.
• W2045702804 date "2014-07-05" @default.
• W2045702804 modified "2023-09-22" @default.
• W2045702804 title "Feasibility and efficacy of induction docetaxel, cisplatin, and 5-fluorouracil chemotherapy combined with concurrent weekly cisplatin chemoradiotherapy for locally advanced head and neck squamous cell carcinoma" @default.
• W2045702804 cites W1974136861 @default.
• W2045702804 cites W1983970003 @default.
• W2045702804 cites W2033200231 @default.
• W2045702804 cites W2035300092 @default.
• W2045702804 cites W2036005555 @default.
• W2045702804 cites W2038158873 @default.
• W2045702804 cites W2063650538 @default.
• W2045702804 cites W2080615931 @default.
• W2045702804 cites W2089257078 @default.
• W2045702804 cites W2096550186 @default.
• W2045702804 cites W2100961085 @default.
• W2045702804 cites W2122252223 @default.
• W2045702804 cites W2122503228 @default.
• W2045702804 cites W2137178561 @default.
• W2045702804 cites W2141592118 @default.
• W2045702804 cites W2150665408 @default.
• W2045702804 cites W2159264690 @default.
• W2045702804 cites W2166349420 @default.
• W2045702804 cites W2171231486 @default.
• W2045702804 doi "https://doi.org/10.1007/s10147-014-0726-y" @default.
• W2045702804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24993675" @default.
• W2045702804 hasPublicationYear "2014" @default.
• W2045702804 type Work @default.
• W2045702804 sameAs 2045702804 @default.
• W2045702804 citedByCount "5" @default.
• W2045702804 countsByYear W20457028042015 @default.
• W2045702804 countsByYear W20457028042016 @default.
• W2045702804 countsByYear W20457028042017 @default.
• W2045702804 countsByYear W20457028042018 @default.
• W2045702804 countsByYear W20457028042020 @default.
• W2045702804 crossrefType "journal-article" @default.
• W2045702804 hasAuthorship W2045702804A5005371127 @default.
• W2045702804 hasAuthorship W2045702804A5020774876 @default.
• W2045702804 hasAuthorship W2045702804A5026356023 @default.
• W2045702804 hasAuthorship W2045702804A5027961713 @default.
• W2045702804 hasAuthorship W2045702804A5028998584 @default.
• W2045702804 hasAuthorship W2045702804A5037474733 @default.
• W2045702804 hasAuthorship W2045702804A5045166286 @default.
• W2045702804 hasAuthorship W2045702804A5045604410 @default.
• W2045702804 hasAuthorship W2045702804A5052320966 @default.
• W2045702804 hasAuthorship W2045702804A5054540480 @default.
• W2045702804 hasAuthorship W2045702804A5055606224 @default.
• W2045702804 hasAuthorship W2045702804A5061496996 @default.
• W2045702804 hasAuthorship W2045702804A5066514747 @default.
• W2045702804 hasAuthorship W2045702804A5072144503 @default.
• W2045702804 hasAuthorship W2045702804A5088707584 @default.
• W2045702804 hasBestOaLocation W20457028042 @default.
• W2045702804 hasConcept C126322002 @default.
• W2045702804 hasConcept C143998085 @default.
• W2045702804 hasConcept C2776530083 @default.
• W2045702804 hasConcept C2776611710 @default.
• W2045702804 hasConcept C2776694085 @default.
• W2045702804 hasConcept C2776833033 @default.
• W2045702804 hasConcept C2777063308 @default.
• W2045702804 hasConcept C2778239845 @default.
• W2045702804 hasConcept C2778424827 @default.
• W2045702804 hasConcept C2778496288 @default.
• W2045702804 hasConcept C2780456651 @default.
• W2045702804 hasConcept C2781190966 @default.
• W2045702804 hasConcept C509974204 @default.
• W2045702804 hasConcept C71924100 @default.
• W2045702804 hasConceptScore W2045702804C126322002 @default.
• W2045702804 hasConceptScore W2045702804C143998085 @default.
• W2045702804 hasConceptScore W2045702804C2776530083 @default.
• W2045702804 hasConceptScore W2045702804C2776611710 @default.
• W2045702804 hasConceptScore W2045702804C2776694085 @default.
• W2045702804 hasConceptScore W2045702804C2776833033 @default.
• W2045702804 hasConceptScore W2045702804C2777063308 @default.
• W2045702804 hasConceptScore W2045702804C2778239845 @default.
• W2045702804 hasConceptScore W2045702804C2778424827 @default.
• W2045702804 hasConceptScore W2045702804C2778496288 @default.
• W2045702804 hasConceptScore W2045702804C2780456651 @default.
• W2045702804 hasConceptScore W2045702804C2781190966 @default.
• W2045702804 hasConceptScore W2045702804C509974204 @default.
• W2045702804 hasConceptScore W2045702804C71924100 @default.
• W2045702804 hasLocation W20457028041 @default.
• W2045702804 hasLocation W20457028042 @default.
• W2045702804 hasLocation W20457028043 @default.
• W2045702804 hasOpenAccess W2045702804 @default.
• W2045702804 hasPrimaryLocation W20457028041 @default.

• next