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• W2045704737 abstract "Exposure of fish to alkaline conditions clearly inhibits the rate of ammonia excretion ( J AMM ) leading to problems of ammonia accumulation and toxicity. There is some evidence that higher environmental calcium levels may ameliorate the negative effects of alkaline exposure. In the present study, we investigated the effects of elevated environmental calcium on the recovery of ammonia excretion during acute (6 h) and chronic (15 day) exposures to high pH (pH 10), and the levels of nitrogenous products (ammonia, urea, and glutamine) in tissues and plasma (1–15 days). Acclimation to alkaline conditions results in a chronically depressed ammonia excretion rate. Glutamine as well as urea do not appear to be important in ammonia detoxification and storage. Calculations of the production rates from storage and excretion data indicate a reduction in the rate of ammonia production. Elevating environmental calcium during acute exposure to alkaline conditions does not affect the recovery of J AMM but may reduce stress. We conclude that rainbow trout survive alkaline exposure by reducing ammonia production and that the role of calcium may be in the amelioration of the stress of alkaline exposure." @default.
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• W2045704737 date "1998-09-01" @default.
• W2045704737 modified "2023-09-25" @default.
• W2045704737 title "Inhibition of ammonia excretion and production in rainbow trout during severe alkaline exposure" @default.
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• W2045704737 doi "https://doi.org/10.1016/s0305-0491(98)10063-9" @default.
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