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- W2045706647 abstract "Sarcosine, an isomer of L-alanine, has been proposed as a prostate cancer progression biomarker [1]. Both compounds are detected in urine, where the measured sarcosine/alanine ratio has been found to be higher in prostate biopsy-positive group versus controls. We present here preliminary evidence showing that urine samples spiked with sarcosine/alanine can be partially resolved in 3 min via tandem differential mobility analysis-mass spectrometry (DMA-MS). Based on the calibration curves obtained for two mobility peaks, we finally estimate their concentration ratio in urine." @default.
- W2045706647 created "2016-06-24" @default.
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- W2045706647 date "2010-07-01" @default.
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- W2045706647 title "Separation of isomers <i>L</i>-alanine and sarcosine in urine by electrospray ionization and tandem differential mobility analysis-mass spectrometry" @default.
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- W2045706647 doi "https://doi.org/10.1016/j.jasms.2010.02.021" @default.
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