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• W2045707929 abstract "Here, we report the identification of yeast 15‐kD Tim15/Zim17, a new member of mitochondrial Hsp70 (mtHsp70)‐associated motor and chaperone (MMC) proteins. The 15‐kD MMC protein is a peripheral inner membrane protein with a zinc‐finger motif. Depletion of the 15‐kD protein led to impaired import of presequence‐containing proteins into the matrix in vivo and in vitro. Overexpression of the 15‐kD protein rescued the functional defects of mtHsp70 in ssc1‐3 cells, and a fusion protein containing the 15‐kD protein physically interacts with purified mtHsp70. Tim15/Zim17 therefore cooperates with mtHsp70 to facilitate import of presequence‐containing proteins into the matrix." @default.
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• W2045707929 date "2004-12-21" @default.
• W2045707929 modified "2023-10-17" @default.
• W2045707929 title "Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane" @default.
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• W2045707929 doi "https://doi.org/10.1016/j.febslet.2004.12.018" @default.
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