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• W2045717400 abstract "This paper proposes and tests an hypothesis to account for the roles of the volume and rate components of vagal feedback in determining the steady-state pattern of breathing during continuous positive pressure breathing (PPB) and expiratory threshold loading (ETL) in Dial anesthetized cats. During PPB the duration of diaphragm activity (Tdi) is shortened; the duration of its expiratory pause (Tep) is lengthened with little or no change in cycle duration (Tt); with onset of inspiration, flow (dV/dt) is increased; as inspiration proceeds, flow decelerates (d2V/dt2). During ETL Tdi, Tep and Tt are all prolonged; dV/dt is decreased at onset of inspiration, with either no change or an acceleration in flow as inspiration proceeds. PPB and ETL cause similar increases in resting lung volume and Tep, and high negative correlations between Tdi and flow. These relationship suggest that the 'volume component' of vagal feedback is one important factor controlling Tep whereas the 'rate component' contributes to the restraint of Tdi." @default.
• W2045717400 created "2016-06-24" @default.
• W2045717400 creator A5076391752 @default.
• W2045717400 date "1977-06-01" @default.
• W2045717400 modified "2023-09-26" @default.
• W2045717400 title "Vagal control of diaphragm timing in cat while breathing at elevated lung volumes" @default.
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• W2045717400 doi "https://doi.org/10.1016/0034-5687(77)90029-9" @default.
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