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• W2045720003 startingPage "pdb.ip068619" @default.
• W2045720003 abstract "Polylysine and its copolymers have been extensively used as nonviral polymeric gene carriers. Although polylysine on its own is toxic to cells, when polyethylene glycol is covalently linked to polylysine, toxicity is reduced and DNA transfection efficiency is increased. A degradable polylysine analog, polyaminobutyl glycolic acid, has been synthesized. Stearyl polylysine shows strong hydrophobic interactions with low-density lipoprotein and these components can be combined with DNA to form a “terplex” system that allows delivery of DNA to targeted cells and significant levels of transfection both in vitro and in vivo." @default.
• W2045720003 created "2016-06-24" @default.
• W2045720003 creator A5078667650 @default.
• W2045720003 date "2012-04-01" @default.
• W2045720003 modified "2023-09-30" @default.
• W2045720003 title "Polylysine Copolymers for Gene Delivery" @default.
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• W2045720003 doi "https://doi.org/10.1101/pdb.ip068619" @default.
• W2045720003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22474666" @default.
• W2045720003 hasPublicationYear "2012" @default.
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