FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045732883> ?p ?o ?g. }

• W2045732883 endingPage "1441" @default.
• W2045732883 startingPage "1430" @default.
• W2045732883 abstract "Lymphoproliferative lesions of the ocular adnexa were analyzed to examine (1) the suitability of the Revised European-American Lymphoma (REAL) classification for the subtyping of the lymphomas in these sites; (2) the predictive value of the REAL classification for the evolution of these tumors; and (3) the frequency and prognostic impact of tumor type, location, proliferation rate (Ki-67 index), p53, CD5 positivity and the presence of monoclonality within these tumors.Retrospective review.The clinical, histomorphologic, immunohistochemical, and molecular biologic (polymerase chain reaction [PCR]) features of lymphoid proliferations of the ocular adnexa were studied. STUDY MATERIALS: The ocular adnexal lymphoproliferative lesions were located as follows: orbit in 52 patients (46%), conjunctiva in 32 patients (29%), eyelid in 23 patients (21%), and caruncle in 5 patients (4%).Reactive lymphoid hyperplasia was diagnosed in 12 cases and lymphoma in 99 cases; 1 case remained indeterminate. The five main subtypes of lymphoma according to the REAL classification were extranodal marginal-zone B-cell lymphoma (64%), follicle center lymphoma (10%), diffuse large cell B-cell lymphoma (9%), plasmacytoma (6%), and lymphoplasmocytic lymphoma (5%). Age, gender, and anatomic localization of the lymphomas did not have prognostic significance during a follow-up period of 6 months to 16.5 years (mean, 3.3 years). Extent of disease at time of presentation was the most important clinical prognostic factor: advanced disease correlated with increased risk ratios of having persistent disease at the final follow-up and with lymphoma-related death (P < 0.001). Histomorphologic features and immunohistochemical markers positively correlating with disseminated disease at presentation, stage at final follow-up, and occurrence of lymphoma-related death included cytologic atypia (P < 0.001), MIB-1 proliferation rate (P < 0.001), and tumor cell p53 positivity (P < 0.001). The MIB-1 proliferation rates greater than 20% in extranodal marginal-zone B-cell lymphoma corresponded to at least stage II lymphoma (P < 0.05).The REAL classification is suitable for the subdivision of the ocular adnexal lymphomas. The MIB-1 proliferation rate and p53 positivity may aid the prediction of disease stage and disease progression, whereas PCR can support the diagnosis and reduce the number of histologically indeterminate lesions." @default.
• W2045732883 created "2016-06-24" @default.
• W2045732883 creator A5009323621 @default.
• W2045732883 creator A5018491022 @default.
• W2045732883 creator A5031298664 @default.
• W2045732883 creator A5036094965 @default.
• W2045732883 creator A5042766411 @default.
• W2045732883 creator A5072765562 @default.
• W2045732883 creator A5074656219 @default.
• W2045732883 creator A5076202901 @default.
• W2045732883 creator A5091740511 @default.
• W2045732883 date "1998-08-01" @default.
• W2045732883 modified "2023-09-25" @default.
• W2045732883 title "Lymphoproliferative lesions of the ocular adnexa" @default.
• W2045732883 cites W1565408903 @default.
• W2045732883 cites W1579476196 @default.
• W2045732883 cites W1585043318 @default.
• W2045732883 cites W1605407171 @default.
• W2045732883 cites W179457243 @default.
• W2045732883 cites W1967745557 @default.
• W2045732883 cites W1967847908 @default.
• W2045732883 cites W1968163150 @default.
• W2045732883 cites W1984004351 @default.
• W2045732883 cites W1986036158 @default.
• W2045732883 cites W1996511380 @default.
• W2045732883 cites W2014799863 @default.
• W2045732883 cites W2016872968 @default.
• W2045732883 cites W2017048220 @default.
• W2045732883 cites W2018368905 @default.
• W2045732883 cites W2019136654 @default.
• W2045732883 cites W2022362740 @default.
• W2045732883 cites W2028847258 @default.
• W2045732883 cites W2032258534 @default.
• W2045732883 cites W2034356013 @default.
• W2045732883 cites W2038252730 @default.
• W2045732883 cites W2043495652 @default.
• W2045732883 cites W2043983872 @default.
• W2045732883 cites W2044716415 @default.
• W2045732883 cites W2046058111 @default.
• W2045732883 cites W2049490710 @default.
• W2045732883 cites W2049851623 @default.
• W2045732883 cites W2052917464 @default.
• W2045732883 cites W2053329190 @default.
• W2045732883 cites W2058488029 @default.
• W2045732883 cites W2060502760 @default.
• W2045732883 cites W2061007663 @default.
• W2045732883 cites W2065411915 @default.
• W2045732883 cites W2067393779 @default.
• W2045732883 cites W2067443503 @default.
• W2045732883 cites W2075696892 @default.
• W2045732883 cites W2077517039 @default.
• W2045732883 cites W2079485481 @default.
• W2045732883 cites W2081142467 @default.
• W2045732883 cites W2086587813 @default.
• W2045732883 cites W2107202569 @default.
• W2045732883 cites W2110186852 @default.
• W2045732883 cites W2114423930 @default.
• W2045732883 cites W2124314287 @default.
• W2045732883 cites W2163963551 @default.
• W2045732883 cites W2248054795 @default.
• W2045732883 cites W2314451028 @default.
• W2045732883 cites W2327775024 @default.
• W2045732883 cites W2332847608 @default.
• W2045732883 cites W2438525767 @default.
• W2045732883 cites W3041047318 @default.
• W2045732883 cites W4239464349 @default.
• W2045732883 cites W4240920161 @default.
• W2045732883 cites W9096930 @default.
• W2045732883 cites W2013287947 @default.
• W2045732883 doi "https://doi.org/10.1016/s0161-6420(98)98024-1" @default.
• W2045732883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9709754" @default.
• W2045732883 hasPublicationYear "1998" @default.
• W2045732883 type Work @default.
• W2045732883 sameAs 2045732883 @default.
• W2045732883 citedByCount "368" @default.
• W2045732883 countsByYear W20457328832012 @default.
• W2045732883 countsByYear W20457328832013 @default.
• W2045732883 countsByYear W20457328832014 @default.
• W2045732883 countsByYear W20457328832015 @default.
• W2045732883 countsByYear W20457328832016 @default.
• W2045732883 countsByYear W20457328832017 @default.
• W2045732883 countsByYear W20457328832018 @default.
• W2045732883 countsByYear W20457328832019 @default.
• W2045732883 countsByYear W20457328832020 @default.
• W2045732883 countsByYear W20457328832021 @default.
• W2045732883 countsByYear W20457328832022 @default.
• W2045732883 countsByYear W20457328832023 @default.
• W2045732883 crossrefType "journal-article" @default.
• W2045732883 hasAuthorship W2045732883A5009323621 @default.
• W2045732883 hasAuthorship W2045732883A5018491022 @default.
• W2045732883 hasAuthorship W2045732883A5031298664 @default.
• W2045732883 hasAuthorship W2045732883A5036094965 @default.
• W2045732883 hasAuthorship W2045732883A5042766411 @default.
• W2045732883 hasAuthorship W2045732883A5072765562 @default.
• W2045732883 hasAuthorship W2045732883A5074656219 @default.
• W2045732883 hasAuthorship W2045732883A5076202901 @default.
• W2045732883 hasAuthorship W2045732883A5091740511 @default.
• W2045732883 hasConcept C126322002 @default.

• next