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- W2045756048 abstract "We have studied the condensation reaction of ImpG† on a poly(C) template, in the presence of various metal ions. With Mg2+ as co-catalyst we confirmed that Pb2+ and Zn2+ are effective catalysts. A catalytic effect was also observed for Bi3+, Sb3+ and Mn2+. Bi3+ and Sn2+, like Pb2+, favored the formation of 2′-5′ linkages. With Mn2+ a rather complex mixture of oligomers is formed, some of which contain pyrophosphate linkages. None of the metal ions investigated behaved like Zn2+ in favoring the formation of the naturally occurring 3′-5′ linkages." @default.
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- W2045756048 date "1980-12-01" @default.
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- W2045756048 title "Template-directed synthesis of oligoguanylates in the presence of metal ions" @default.
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- W2045756048 doi "https://doi.org/10.1016/0022-2836(80)90338-1" @default.
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