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• W2045762079 startingPage "422" @default.
• W2045762079 abstract "ABSTRACT The aril of the plant Myristica fragrans is one of the most broadly used spices in Moroccan gastronomy. This research demonstrated its antimicrobial activity against both gram‐positive and gram‐negative bacterial species. Likewise, its toxicity was investigated on Swiss albino mice. Mice were treated orally with 0.003 and 0.3 mg/day during 7 days. Plasmatic markers and antioxidant defense systems were assessed and histological alterations evaluated. Our results showed a significant increase in creatine phosphokinase level. The microscopic evaluation showed that mace induces morphological perturbation in mice's liver. The results also showed an inhibitory effect of glyceraldehyde 3‐phosphate dehydrogenase and an important increase in the level of thiobarbituric acid reactive substances, succinate dehydrogenase activities and no change in catalase activities. All of these results show that M. fragrans at 0.3 mg/g in mice affects energy metabolism and oxidative stress. PRACTICAL APPLICATIONS Mace can be used as a natural antioxidant and preservative in the food industry to increase the shelf life of foodstuffs." @default.
• W2045762079 created "2016-06-24" @default.
• W2045762079 creator A5003430510 @default.
• W2045762079 creator A5053245243 @default.
• W2045762079 creator A5072862793 @default.
• W2045762079 date "2008-07-28" @default.
• W2045762079 modified "2023-10-18" @default.
• W2045762079 title "TOXICITY AND ANTIBACTERIAL EFFECT OF MACE OF<i>MYRISTICA FRAGRANS</i>USED IN MOROCCAN GASTRONOMY: BIOCHEMICAL AND HISTOLOGICAL IMPACT" @default.
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• W2045762079 doi "https://doi.org/10.1111/j.1745-4565.2008.00110.x" @default.
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