FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045770872> ?p ?o ?g. }

• W2045770872 endingPage "231" @default.
• W2045770872 startingPage "220" @default.
• W2045770872 abstract "Functional interrelationships between components of nuclear architecture and control of gene expression are becoming increasingly evident. There is growing appreciation that multiple levels of nuclear organization integrate the regulatory cues that support activation and suppression of genes as well as the processing of gene transcripts. The linear organization of genes and promoter elements provide the potential for responsiveness to physiological regulatory signals. Parameters of chromatin structure and nucleosome organization support synergism between activities at independent regulatory sequences and render promoter elements accessible or refractory to transcription factors. Association of genes, transcription factors, and the machinery for transcript processing with the nuclear matrix facilitates fidelity of gene expression within the three-dimensional context of nuclear architecture. Mechanisms must be defined that couple nuclear morphology with enzymatic parameters of gene expression. The recent characterization of factors that mediate chromatin remodeling and intranuclear targeting signals that direct transcription factors to subnuclear domains where gene expression occurs, reflect linkage of genetic and structural components of transcriptional control. Nuclear reorganization and aberrant intranuclear trafficking of transcription factors for developmental and tissue-specific control that occurs in tumor cells and in neurological disorders provides a basis for high resolution diagnostic and targeted therapy." @default.
• W2045770872 created "2016-06-24" @default.
• W2045770872 creator A5008755139 @default.
• W2045770872 creator A5019883352 @default.
• W2045770872 creator A5031362021 @default.
• W2045770872 creator A5061033022 @default.
• W2045770872 creator A5066298772 @default.
• W2045770872 creator A5081119848 @default.
• W2045770872 date "1998-01-01" @default.
• W2045770872 modified "2023-10-18" @default.
• W2045770872 title "Linkages of nuclear architecture to biological and pathological control of gene expression" @default.
• W2045770872 cites W1622884348 @default.
• W2045770872 cites W17703454 @default.
• W2045770872 cites W1945687446 @default.
• W2045770872 cites W1963652893 @default.
• W2045770872 cites W1964484547 @default.
• W2045770872 cites W1966320246 @default.
• W2045770872 cites W1968066029 @default.
• W2045770872 cites W1971095040 @default.
• W2045770872 cites W1971458488 @default.
• W2045770872 cites W1975647987 @default.
• W2045770872 cites W1976327299 @default.
• W2045770872 cites W1977119229 @default.
• W2045770872 cites W1989308870 @default.
• W2045770872 cites W1993937892 @default.
• W2045770872 cites W1994596418 @default.
• W2045770872 cites W1998475589 @default.
• W2045770872 cites W2003521210 @default.
• W2045770872 cites W2003617876 @default.
• W2045770872 cites W2004608686 @default.
• W2045770872 cites W2006048118 @default.
• W2045770872 cites W2011820716 @default.
• W2045770872 cites W2012945637 @default.
• W2045770872 cites W2013064216 @default.
• W2045770872 cites W2023412673 @default.
• W2045770872 cites W2032040015 @default.
• W2045770872 cites W2044051238 @default.
• W2045770872 cites W2051525713 @default.
• W2045770872 cites W2053733046 @default.
• W2045770872 cites W2057296050 @default.
• W2045770872 cites W2059109691 @default.
• W2045770872 cites W2060199527 @default.
• W2045770872 cites W2062438194 @default.
• W2045770872 cites W2062766739 @default.
• W2045770872 cites W2065422635 @default.
• W2045770872 cites W2075027785 @default.
• W2045770872 cites W2075529268 @default.
• W2045770872 cites W2077150554 @default.
• W2045770872 cites W2080602316 @default.
• W2045770872 cites W2083028663 @default.
• W2045770872 cites W2084937656 @default.
• W2045770872 cites W2087181226 @default.
• W2045770872 cites W2089909407 @default.
• W2045770872 cites W2109943424 @default.
• W2045770872 cites W2113086962 @default.
• W2045770872 cites W2124597426 @default.
• W2045770872 cites W2130002948 @default.
• W2045770872 cites W2140791473 @default.
• W2045770872 cites W2155512899 @default.
• W2045770872 cites W2158242249 @default.
• W2045770872 cites W2165787335 @default.
• W2045770872 cites W2166024044 @default.
• W2045770872 cites W2166907165 @default.
• W2045770872 cites W2169522866 @default.
• W2045770872 cites W2170425393 @default.
• W2045770872 cites W2171204713 @default.
• W2045770872 cites W2344829482 @default.
• W2045770872 cites W4255146022 @default.
• W2045770872 cites W4299346960 @default.
• W2045770872 cites W78763444 @default.
• W2045770872 doi "https://doi.org/10.1002/(sici)1097-4644(1998)72:30/31+<220::aid-jcb27>3.0.co;2-w" @default.
• W2045770872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9893274" @default.
• W2045770872 hasPublicationYear "1998" @default.
• W2045770872 type Work @default.
• W2045770872 sameAs 2045770872 @default.
• W2045770872 citedByCount "7" @default.
• W2045770872 countsByYear W20457708722014 @default.
• W2045770872 crossrefType "journal-article" @default.
• W2045770872 hasAuthorship W2045770872A5008755139 @default.
• W2045770872 hasAuthorship W2045770872A5019883352 @default.
• W2045770872 hasAuthorship W2045770872A5031362021 @default.
• W2045770872 hasAuthorship W2045770872A5061033022 @default.
• W2045770872 hasAuthorship W2045770872A5066298772 @default.
• W2045770872 hasAuthorship W2045770872A5081119848 @default.
• W2045770872 hasConcept C101762097 @default.
• W2045770872 hasConcept C104317684 @default.
• W2045770872 hasConcept C105686024 @default.
• W2045770872 hasConcept C138885662 @default.
• W2045770872 hasConcept C150194340 @default.
• W2045770872 hasConcept C165864922 @default.
• W2045770872 hasConcept C167227067 @default.
• W2045770872 hasConcept C172407341 @default.
• W2045770872 hasConcept C179926584 @default.
• W2045770872 hasConcept C41895202 @default.
• W2045770872 hasConcept C54355233 @default.
• W2045770872 hasConcept C70721500 @default.
• W2045770872 hasConcept C83640560 @default.
• W2045770872 hasConcept C86339819 @default.

• next