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- W2045782003 abstract "The first asymmetric synthesis of some novel substituted 1,4-dihydropyridines (1,4-DHPs) is reported. The synthetic methodology used is based on the Michael addition of β-aminocrotonates to chiral α-acetylacrylates, readily available from chiral aldehydes, leading to the 1,4-DHPs in excellent diastereoselectivity. A Felkin-Ahn model is proposed for the generation of the new stereocenter (C-4) whose absolute configuration has been established as S by X-Ray analysis." @default.
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- W2045782003 date "1995-04-01" @default.
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- W2045782003 title "Asymmetric synthesis of 4-alkyl-3,5-dialkoxycarbonyl-2,6-dimethyl-1,4-dihydropyridines" @default.
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- W2045782003 doi "https://doi.org/10.1016/0957-4166(95)00094-6" @default.
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