Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045785090> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2045785090 endingPage "210" @default.
- W2045785090 startingPage "207" @default.
- W2045785090 abstract "Umbilical cord blood and tissue were obtained at hysterotomy from human fetuses of 8–20 weeks gestation along with maternal peripheral blood. Umbilical cord and maternal blood were also obtained from healthy newborn babies and their mothers after spontaneous delivery. The samples were analyzed by competitive binding to human sex steroid-binding globulin to determine the total levels of unconjugated 17ß-hydroxysteroids and, after column chromatography, testosterone (T). Androgen levels of maternal serum (20 ng/ml) both in mid-pregnancy and at parturition were much higher than those of non-pregnant women (1–8 ng/ml) but T was only slightly elevated (0.98 vs 0.37 ng/ml). Cord serum levels of total androgens in both male and female fetuses did not differ from maternal levels at the time of parturition but were lower in early gestation. Male cord serum at 8–18 weeks showed a higher level of T(3–7 ng/ml) than serum from females, newborn males or mothers. Testicular androgens were greatly elevated (2900 ng/g) compared with adrenal (214 ng/g or ovarian (272 ng/g) levels. The bulk of this material in the testis was testosterone. Thus the mean testicular level (1730 ng/g) was about 500 × the serum T level (3.7 ng/ml). There was relatively little material identifiable as. Tin the ovaries of any of the female fetuses studied(< 40 ng/g) or in the adrenal glands of fetuses of either sex (148 ng/g). It is concluded that the human fetal testis undergoes a period of intense secretory activity during early gestation but is relatively quiescent at birth." @default.
- W2045785090 created "2016-06-24" @default.
- W2045785090 creator A5001456530 @default.
- W2045785090 creator A5014571512 @default.
- W2045785090 date "1974-05-01" @default.
- W2045785090 modified "2023-09-27" @default.
- W2045785090 title "Androgens in the human fetus" @default.
- W2045785090 cites W1571559996 @default.
- W2045785090 cites W1976671560 @default.
- W2045785090 cites W1982679023 @default.
- W2045785090 cites W2014277170 @default.
- W2045785090 cites W2014972178 @default.
- W2045785090 cites W2030175101 @default.
- W2045785090 cites W2065162906 @default.
- W2045785090 cites W2079104974 @default.
- W2045785090 doi "https://doi.org/10.1016/0022-4731(74)90133-2" @default.
- W2045785090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4368413" @default.
- W2045785090 hasPublicationYear "1974" @default.
- W2045785090 type Work @default.
- W2045785090 sameAs 2045785090 @default.
- W2045785090 citedByCount "50" @default.
- W2045785090 countsByYear W20457850902012 @default.
- W2045785090 countsByYear W20457850902013 @default.
- W2045785090 countsByYear W20457850902014 @default.
- W2045785090 crossrefType "journal-article" @default.
- W2045785090 hasAuthorship W2045785090A5001456530 @default.
- W2045785090 hasAuthorship W2045785090A5014571512 @default.
- W2045785090 hasConcept C126322002 @default.
- W2045785090 hasConcept C134018914 @default.
- W2045785090 hasConcept C172680121 @default.
- W2045785090 hasConcept C203014093 @default.
- W2045785090 hasConcept C2776955114 @default.
- W2045785090 hasConcept C2777407945 @default.
- W2045785090 hasConcept C2777911890 @default.
- W2045785090 hasConcept C2779234561 @default.
- W2045785090 hasConcept C2779279991 @default.
- W2045785090 hasConcept C2780914630 @default.
- W2045785090 hasConcept C46973012 @default.
- W2045785090 hasConcept C54355233 @default.
- W2045785090 hasConcept C71315377 @default.
- W2045785090 hasConcept C71924100 @default.
- W2045785090 hasConcept C86803240 @default.
- W2045785090 hasConceptScore W2045785090C126322002 @default.
- W2045785090 hasConceptScore W2045785090C134018914 @default.
- W2045785090 hasConceptScore W2045785090C172680121 @default.
- W2045785090 hasConceptScore W2045785090C203014093 @default.
- W2045785090 hasConceptScore W2045785090C2776955114 @default.
- W2045785090 hasConceptScore W2045785090C2777407945 @default.
- W2045785090 hasConceptScore W2045785090C2777911890 @default.
- W2045785090 hasConceptScore W2045785090C2779234561 @default.
- W2045785090 hasConceptScore W2045785090C2779279991 @default.
- W2045785090 hasConceptScore W2045785090C2780914630 @default.
- W2045785090 hasConceptScore W2045785090C46973012 @default.
- W2045785090 hasConceptScore W2045785090C54355233 @default.
- W2045785090 hasConceptScore W2045785090C71315377 @default.
- W2045785090 hasConceptScore W2045785090C71924100 @default.
- W2045785090 hasConceptScore W2045785090C86803240 @default.
- W2045785090 hasIssue "3" @default.
- W2045785090 hasLocation W20457850901 @default.
- W2045785090 hasLocation W20457850902 @default.
- W2045785090 hasOpenAccess W2045785090 @default.
- W2045785090 hasPrimaryLocation W20457850901 @default.
- W2045785090 hasRelatedWork W1965833776 @default.
- W2045785090 hasRelatedWork W1977493149 @default.
- W2045785090 hasRelatedWork W1979452793 @default.
- W2045785090 hasRelatedWork W1981433740 @default.
- W2045785090 hasRelatedWork W1986311037 @default.
- W2045785090 hasRelatedWork W1993795923 @default.
- W2045785090 hasRelatedWork W2039466440 @default.
- W2045785090 hasRelatedWork W2053247908 @default.
- W2045785090 hasRelatedWork W2083564258 @default.
- W2045785090 hasRelatedWork W2089368232 @default.
- W2045785090 hasVolume "5" @default.
- W2045785090 isParatext "false" @default.
- W2045785090 isRetracted "false" @default.
- W2045785090 magId "2045785090" @default.
- W2045785090 workType "article" @default.