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- W2045792291 endingPage "591" @default.
- W2045792291 startingPage "581" @default.
- W2045792291 abstract "Cell competition occurs when cells that grow at different rates confront each other. This results in the elimination of the slower growing cells by apoptosis. Although exactly how this occurs is unclear, mechanical factors might be involved, as cell crowding within an epithelium leads to delamination and extrusion. When fast-growing cells are confronted with slow-growing cells in a mosaic tissue, the slow-growing cells are often progressively eliminated by apoptosis through a process known as cell competition. The underlying signalling pathways remain unknown, but recent findings have shown that cell crowding within an epithelium leads to the eviction of cells from the epithelial sheet. This suggests that mechanical forces could contribute to cell elimination during cell competition." @default.
- W2045792291 created "2016-06-24" @default.
- W2045792291 creator A5026910783 @default.
- W2045792291 creator A5047765555 @default.
- W2045792291 creator A5061953464 @default.
- W2045792291 date "2013-08-14" @default.
- W2045792291 modified "2023-10-14" @default.
- W2045792291 title "Mechanisms and mechanics of cell competition in epithelia" @default.
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