FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045802581> ?p ?o ?g. }

• W2045802581 endingPage "660" @default.
• W2045802581 startingPage "650" @default.
• W2045802581 abstract "The microfold (M) cell residing in the follicle-associated epithelium is a specialized epithelial cell that initiates mucosal immune responses by sampling luminal antigens. The differentiation process of M cells remains unclear due to limitations of analytical methods. Here we found that M cells were classified into two functionally different subtypes based on the expression of Glycoprotein 2 (GP2) by newly developed image cytometric analysis. GP2-high M cells actively took up luminal microbeads, whereas GP2-negative or low cells scarcely ingested them, even though both subsets equally expressed the other M-cell signature genes, suggesting that GP2-high M cells represent functionally mature M cells. Further, the GP2-high mature M cells were abundant in Peyer's patch but sparse in the cecal patch: this was most likely due to a decrease in the nuclear translocation of RelB, a downstream transcription factor for the receptor activator of nuclear factor-κB signaling. Given that murine cecum contains a protrusion of beneficial commensals, the restriction of M-cell activity might contribute to preventing the onset of any excessive immune response to the commensals through decelerating the M-cell-dependent uptake of microorganisms." @default.
• W2045802581 created "2016-06-24" @default.
• W2045802581 creator A5027603182 @default.
• W2045802581 creator A5037493397 @default.
• W2045802581 creator A5051079614 @default.
• W2045802581 creator A5057187893 @default.
• W2045802581 creator A5074965316 @default.
• W2045802581 creator A5080702325 @default.
• W2045802581 creator A5081645142 @default.
• W2045802581 date "2015-05-01" @default.
• W2045802581 modified "2023-10-16" @default.
• W2045802581 title "Visualization of the entire differentiation process of murine M cells: suppression of their maturation in cecal patches" @default.
• W2045802581 cites W1558901013 @default.
• W2045802581 cites W1777407783 @default.
• W2045802581 cites W1911063200 @default.
• W2045802581 cites W1955079753 @default.
• W2045802581 cites W1968291110 @default.
• W2045802581 cites W1970444129 @default.
• W2045802581 cites W1977859620 @default.
• W2045802581 cites W1984700814 @default.
• W2045802581 cites W1986711154 @default.
• W2045802581 cites W1988102812 @default.
• W2045802581 cites W2001279129 @default.
• W2045802581 cites W2001712372 @default.
• W2045802581 cites W2007518207 @default.
• W2045802581 cites W2015086458 @default.
• W2045802581 cites W2035177961 @default.
• W2045802581 cites W2035423923 @default.
• W2045802581 cites W2043246560 @default.
• W2045802581 cites W2082691432 @default.
• W2045802581 cites W2085355903 @default.
• W2045802581 cites W2099540110 @default.
• W2045802581 cites W2100877397 @default.
• W2045802581 cites W2109325879 @default.
• W2045802581 cites W2116339721 @default.
• W2045802581 cites W2130079153 @default.
• W2045802581 cites W2137652355 @default.
• W2045802581 cites W2140489687 @default.
• W2045802581 cites W2142072948 @default.
• W2045802581 cites W2153516407 @default.
• W2045802581 cites W50975393 @default.
• W2045802581 doi "https://doi.org/10.1038/mi.2014.99" @default.
• W2045802581 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25336168" @default.
• W2045802581 hasPublicationYear "2015" @default.
• W2045802581 type Work @default.
• W2045802581 sameAs 2045802581 @default.
• W2045802581 citedByCount "55" @default.
• W2045802581 countsByYear W20458025812015 @default.
• W2045802581 countsByYear W20458025812016 @default.
• W2045802581 countsByYear W20458025812017 @default.
• W2045802581 countsByYear W20458025812018 @default.
• W2045802581 countsByYear W20458025812019 @default.
• W2045802581 countsByYear W20458025812020 @default.
• W2045802581 countsByYear W20458025812021 @default.
• W2045802581 countsByYear W20458025812022 @default.
• W2045802581 countsByYear W20458025812023 @default.
• W2045802581 crossrefType "journal-article" @default.
• W2045802581 hasAuthorship W2045802581A5027603182 @default.
• W2045802581 hasAuthorship W2045802581A5037493397 @default.
• W2045802581 hasAuthorship W2045802581A5051079614 @default.
• W2045802581 hasAuthorship W2045802581A5057187893 @default.
• W2045802581 hasAuthorship W2045802581A5074965316 @default.
• W2045802581 hasAuthorship W2045802581A5080702325 @default.
• W2045802581 hasAuthorship W2045802581A5081645142 @default.
• W2045802581 hasBestOaLocation W20458025811 @default.
• W2045802581 hasConcept C104317684 @default.
• W2045802581 hasConcept C123298856 @default.
• W2045802581 hasConcept C147483822 @default.
• W2045802581 hasConcept C1491633281 @default.
• W2045802581 hasConcept C203014093 @default.
• W2045802581 hasConcept C2777453290 @default.
• W2045802581 hasConcept C2778019737 @default.
• W2045802581 hasConcept C43667030 @default.
• W2045802581 hasConcept C529295009 @default.
• W2045802581 hasConcept C54355233 @default.
• W2045802581 hasConcept C86339819 @default.
• W2045802581 hasConcept C86803240 @default.
• W2045802581 hasConcept C8891405 @default.
• W2045802581 hasConcept C95444343 @default.
• W2045802581 hasConceptScore W2045802581C104317684 @default.
• W2045802581 hasConceptScore W2045802581C123298856 @default.
• W2045802581 hasConceptScore W2045802581C147483822 @default.
• W2045802581 hasConceptScore W2045802581C1491633281 @default.
• W2045802581 hasConceptScore W2045802581C203014093 @default.
• W2045802581 hasConceptScore W2045802581C2777453290 @default.
• W2045802581 hasConceptScore W2045802581C2778019737 @default.
• W2045802581 hasConceptScore W2045802581C43667030 @default.
• W2045802581 hasConceptScore W2045802581C529295009 @default.
• W2045802581 hasConceptScore W2045802581C54355233 @default.
• W2045802581 hasConceptScore W2045802581C86339819 @default.
• W2045802581 hasConceptScore W2045802581C86803240 @default.
• W2045802581 hasConceptScore W2045802581C8891405 @default.
• W2045802581 hasConceptScore W2045802581C95444343 @default.
• W2045802581 hasIssue "3" @default.
• W2045802581 hasLocation W20458025811 @default.
• W2045802581 hasLocation W20458025812 @default.
• W2045802581 hasLocation W20458025813 @default.
• W2045802581 hasOpenAccess W2045802581 @default.

• next