FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045804567> ?p ?o ?g. }

• W2045804567 endingPage "641" @default.
• W2045804567 startingPage "629" @default.
• W2045804567 abstract "Acute renal failure (ARF) is a broad clinical entity, encompassing diverse pathophysiologies, with heterogeneous functional and morphological features. In the same fashion, various animal models of ARF differ in their mechanisms, distribution and type of injury, cellular responses and outcome.To appraise available animal models of ARF used for the assessment of potential therapeutic interventions, providing their basic pathophysiologies.Review of literature and summaries of expert opinion discussion forums.Various animal models of ARF are used for the development of therapeutic/preventive interventions, including toxic, hypoxic and septic models. Incomplete understanding of the outstanding complexity of human ARF often leads to too simplistic interventional concepts or to misconceptions, based on models with limited clinical relevance. Thus, for the appropriateness of animal models, the use of models inflicting severe injury, though highly reproducible and consistent, should be weighted against more clinically relevant models. Such models often consist of milder insults, supplemented with the induction of predisposing factors or supportive measures, encountered in the clinical practice. In the perspective of the compound pathogenesis of ARF, assessment of the degree of renal dysfunction is not enough as a single end point, and should be complemented by the evaluation of parameters such as renal microcirculation, oxygenation, cellular adaptive response and morphology. New imaging technologies and biomarkers bring about new insight in this evolving field." @default.
• W2045804567 created "2016-06-24" @default.
• W2045804567 creator A5016125913 @default.
• W2045804567 creator A5033696250 @default.
• W2045804567 creator A5065292902 @default.
• W2045804567 date "2009-05-06" @default.
• W2045804567 modified "2023-10-13" @default.
• W2045804567 title "Animal models of renal dysfunction: acute kidney injury" @default.
• W2045804567 cites W1515719090 @default.
• W2045804567 cites W1592707978 @default.
• W2045804567 cites W1964371038 @default.
• W2045804567 cites W1967469976 @default.
• W2045804567 cites W1971794803 @default.
• W2045804567 cites W1977331927 @default.
• W2045804567 cites W1980489046 @default.
• W2045804567 cites W1980743616 @default.
• W2045804567 cites W1981277735 @default.
• W2045804567 cites W1982628508 @default.
• W2045804567 cites W1984233328 @default.
• W2045804567 cites W1990892782 @default.
• W2045804567 cites W1991416315 @default.
• W2045804567 cites W1992920273 @default.
• W2045804567 cites W1995190701 @default.
• W2045804567 cites W1995615536 @default.
• W2045804567 cites W2002382863 @default.
• W2045804567 cites W2007032123 @default.
• W2045804567 cites W2010668846 @default.
• W2045804567 cites W2013526450 @default.
• W2045804567 cites W2015051872 @default.
• W2045804567 cites W2017415809 @default.
• W2045804567 cites W2018128965 @default.
• W2045804567 cites W2019975627 @default.
• W2045804567 cites W2025385597 @default.
• W2045804567 cites W2027917795 @default.
• W2045804567 cites W2035251186 @default.
• W2045804567 cites W2035433014 @default.
• W2045804567 cites W2035637304 @default.
• W2045804567 cites W2042882901 @default.
• W2045804567 cites W2044138368 @default.
• W2045804567 cites W2045857514 @default.
• W2045804567 cites W2046077452 @default.
• W2045804567 cites W2047111978 @default.
• W2045804567 cites W2066462534 @default.
• W2045804567 cites W2069722312 @default.
• W2045804567 cites W2079360289 @default.
• W2045804567 cites W2079506211 @default.
• W2045804567 cites W2080248015 @default.
• W2045804567 cites W2087616812 @default.
• W2045804567 cites W2089755055 @default.
• W2045804567 cites W2093316059 @default.
• W2045804567 cites W2095112808 @default.
• W2045804567 cites W2097271403 @default.
• W2045804567 cites W2107301293 @default.
• W2045804567 cites W2108352961 @default.
• W2045804567 cites W2109531898 @default.
• W2045804567 cites W2110664459 @default.
• W2045804567 cites W2118357438 @default.
• W2045804567 cites W2119741487 @default.
• W2045804567 cites W2126829153 @default.
• W2045804567 cites W2127477439 @default.
• W2045804567 cites W2127645629 @default.
• W2045804567 cites W2129530834 @default.
• W2045804567 cites W2130348420 @default.
• W2045804567 cites W2132444412 @default.
• W2045804567 cites W2133157501 @default.
• W2045804567 cites W2133254081 @default.
• W2045804567 cites W2136438262 @default.
• W2045804567 cites W2139529386 @default.
• W2045804567 cites W2144351923 @default.
• W2045804567 cites W2150737557 @default.
• W2045804567 cites W2152077380 @default.
• W2045804567 cites W2154068227 @default.
• W2045804567 cites W2155441599 @default.
• W2045804567 cites W2155984934 @default.
• W2045804567 cites W2157105773 @default.
• W2045804567 cites W2157381559 @default.
• W2045804567 cites W2160785366 @default.
• W2045804567 cites W2161522720 @default.
• W2045804567 cites W2166103710 @default.
• W2045804567 cites W2166545060 @default.
• W2045804567 cites W2170355346 @default.
• W2045804567 cites W2291307933 @default.
• W2045804567 cites W2317491188 @default.
• W2045804567 cites W2413267052 @default.
• W2045804567 cites W248555676 @default.
• W2045804567 cites W2913091595 @default.
• W2045804567 cites W4237767968 @default.
• W2045804567 cites W4250210754 @default.
• W2045804567 doi "https://doi.org/10.1517/17460440902946389" @default.
• W2045804567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23489156" @default.
• W2045804567 hasPublicationYear "2009" @default.
• W2045804567 type Work @default.
• W2045804567 sameAs 2045804567 @default.
• W2045804567 citedByCount "31" @default.
• W2045804567 countsByYear W20458045672015 @default.
• W2045804567 countsByYear W20458045672016 @default.
• W2045804567 countsByYear W20458045672017 @default.
• W2045804567 countsByYear W20458045672018 @default.

• next