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- W2045806467 abstract "This volume presents the proceedings of the Sixth Capo Boi Conference on Neuroscience, held in Villasimius, Italy, in June 1989. The structural heterogeneity of the γ-aminobutyric acid (GABA) A receptor and its possible impact on discrete functional differences between receptor variants is discussed in great detail. The allosteric modulation of the receptor-anion channel function by the benzodiazepine receptor is discussed at the molecular level. During the past 5 years, the progress of our understanding of the GABAergic synaptic function has contributed a structural complexity. Since the GABA A receptor constitutes subunits, determining its molecular characteristics and how the different subunits interact has been a difficult problem that has just recently been solved. Assessing whether or not all possible combinations of the GABA A receptor subtypes are expressed and functional is the focus of this volume. The benzodiazepine binding sites are no longer exclusively linked to GABAergic function. With the cloning" @default.
- W2045806467 created "2016-06-24" @default.
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- W2045806467 date "1991-11-01" @default.
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- W2045806467 title "Advances in Biochemical Psychopharmacology: GABA and Benzodiazepine Receptor Subtypes: Molecular Biology, Pharmacology, and Clinical Aspects" @default.
- W2045806467 doi "https://doi.org/10.1001/archneur.1991.00530230022008" @default.
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