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- W2045807823 abstract "Objective: To study the disruption of co-localization of human Daxx(hDaxx) with promyelocytic leukemia protein(PML) at the PML oncogenic domains (PODs) by the interaction of hDaxx with adenovirus(Ad) 12 E1B 55 Kilodalton Oncoprotein (Ad 12 E1B 55kD). Methods: The direct binding reaction of hDaxx and Ad12 E1B 55kD was analyzed by coimmunoprecipitation and Western blottingin vivo orin vitro. The interaction of hDaxx with Ad12 E1B 55kD was studied using yeast two-hybrid assay. Results: hDaxx bounded directly to Ad12 E1B 55kDin vivo andin vitro. hDaxx interacted with full length Ad12 E1B 55kD. Conclusion: Transcriptional regulator hDaxx directly binds to and interacts with Ad12 E1B 55kD." @default.
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- W2045807823 date "2003-12-01" @default.
- W2045807823 modified "2023-09-26" @default.
- W2045807823 title "Binding and interaction of transcriptional regulator human Daxx with adenovirus12 E1B 55 kilodalton oncoprotein" @default.
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- W2045807823 doi "https://doi.org/10.1007/bf02974891" @default.
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