FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045857503> ?p ?o ?g. }

• W2045857503 endingPage "93" @default.
• W2045857503 startingPage "73" @default.
• W2045857503 abstract "Reports of prenatal ethanol (ETOH) effects on the dopamine system are inconsistent. In an attempt to clarify this issue, dams were given 35% ethanol-derived calories as the sole nutrient source in a liquid diet from the 10th through the 20th day of gestation (ETOH). Controls were pair-fed (PF) an isocaloric liquid diet or given ad libitum access to laboratory chow (LC). Prenatal exposure to both liquid diets reduced body weight of offspring relative to LC controls, more so for ETOH than for PF exposure. Prenatal ETOH also decreased litter size and viability, relative to both LC and PF control groups. On postnatal days 21–23, male and female offspring were given an injection of saline vehicle or one of eight specific dopamine receptor agonists or antagonists. Immediately after injection subjects were placed in individual observation cages, and over the following 30 min, eight behaviors (square entries, grooming, rearing, circling, sniffing, yawning, head and oral movements) were observed and quantified. No prenatal treatment effects on drug-induced behaviors were observed for dopamine D2 (Apomorphine, DPAT or Quinpirole) or D3 (PD 152255, Nafadotride, Apo or Quin effects on yawning) receptor agonists or antagonists, or for the vehicle control. In contrast, prenatal treatment effects were seen with drugs affecting the dopamine D1 receptor. Both D1 agonists (SKF 38393) and antagonists (SCH 23390 and high doses of spiperone) altered behaviors, especially oral and sniffing behaviors, in a manner which suggested enhanced dopamine D1 drug sensitivity in both ETOH and PF offspring relative to LC controls. These results suggest that at this age, both sexes experience a prenatal undernutrition-linked increase in the behavioral response to dopamine D1 agonists and antagonists, which can be intensified by gestational exposure to alcohol." @default.
• W2045857503 created "2016-06-24" @default.
• W2045857503 creator A5014016597 @default.
• W2045857503 creator A5021593234 @default.
• W2045857503 creator A5021867318 @default.
• W2045857503 creator A5060857229 @default.
• W2045857503 creator A5085254151 @default.
• W2045857503 date "2005-01-01" @default.
• W2045857503 modified "2023-09-26" @default.
• W2045857503 title "Prenatal ethanol preferentially enhances reactivity of the dopamine D1 but not D2 or D3 receptors in offspring" @default.
• W2045857503 cites W1568416177 @default.
• W2045857503 cites W1582206225 @default.
• W2045857503 cites W1966360491 @default.
• W2045857503 cites W1966607328 @default.
• W2045857503 cites W1968434103 @default.
• W2045857503 cites W1970757243 @default.
• W2045857503 cites W1971865743 @default.
• W2045857503 cites W1972782117 @default.
• W2045857503 cites W1974506268 @default.
• W2045857503 cites W1975024858 @default.
• W2045857503 cites W1975887697 @default.
• W2045857503 cites W1976403478 @default.
• W2045857503 cites W1978512984 @default.
• W2045857503 cites W1979565994 @default.
• W2045857503 cites W1982176417 @default.
• W2045857503 cites W1983125567 @default.
• W2045857503 cites W1983332108 @default.
• W2045857503 cites W1983429515 @default.
• W2045857503 cites W1987913422 @default.
• W2045857503 cites W1988275850 @default.
• W2045857503 cites W1989171920 @default.
• W2045857503 cites W1991162197 @default.
• W2045857503 cites W1991583138 @default.
• W2045857503 cites W1992078791 @default.
• W2045857503 cites W1993403597 @default.
• W2045857503 cites W1994046905 @default.
• W2045857503 cites W1994353461 @default.
• W2045857503 cites W1994441545 @default.
• W2045857503 cites W1994642861 @default.
• W2045857503 cites W1995534964 @default.
• W2045857503 cites W1999180056 @default.
• W2045857503 cites W1999290364 @default.
• W2045857503 cites W2001687421 @default.
• W2045857503 cites W2002583999 @default.
• W2045857503 cites W2003888341 @default.
• W2045857503 cites W2005621090 @default.
• W2045857503 cites W2006883175 @default.
• W2045857503 cites W2009069617 @default.
• W2045857503 cites W2009355260 @default.
• W2045857503 cites W2018526785 @default.
• W2045857503 cites W2019019221 @default.
• W2045857503 cites W2022367194 @default.
• W2045857503 cites W2022395708 @default.
• W2045857503 cites W2024936720 @default.
• W2045857503 cites W2027383673 @default.
• W2045857503 cites W2029624783 @default.
• W2045857503 cites W2030223167 @default.
• W2045857503 cites W2031145937 @default.
• W2045857503 cites W2032578858 @default.
• W2045857503 cites W2033542005 @default.
• W2045857503 cites W2035122767 @default.
• W2045857503 cites W2036816692 @default.
• W2045857503 cites W2038852848 @default.
• W2045857503 cites W2041114226 @default.
• W2045857503 cites W2041516350 @default.
• W2045857503 cites W2042505228 @default.
• W2045857503 cites W2044610512 @default.
• W2045857503 cites W2044921280 @default.
• W2045857503 cites W2049335763 @default.
• W2045857503 cites W2050691698 @default.
• W2045857503 cites W2050706997 @default.
• W2045857503 cites W2052291545 @default.
• W2045857503 cites W2054028081 @default.
• W2045857503 cites W2054713967 @default.
• W2045857503 cites W2055710370 @default.
• W2045857503 cites W2056167795 @default.
• W2045857503 cites W2056796787 @default.
• W2045857503 cites W2057612940 @default.
• W2045857503 cites W2057683939 @default.
• W2045857503 cites W2058022562 @default.
• W2045857503 cites W2059707255 @default.
• W2045857503 cites W2061677744 @default.
• W2045857503 cites W2061732252 @default.
• W2045857503 cites W2062148376 @default.
• W2045857503 cites W2065491717 @default.
• W2045857503 cites W2066014487 @default.
• W2045857503 cites W2067544517 @default.
• W2045857503 cites W2069170641 @default.
• W2045857503 cites W2070805027 @default.
• W2045857503 cites W2071987531 @default.
• W2045857503 cites W2072013663 @default.
• W2045857503 cites W2073190252 @default.
• W2045857503 cites W2075346463 @default.
• W2045857503 cites W2076089389 @default.
• W2045857503 cites W2076668541 @default.
• W2045857503 cites W2077539849 @default.
• W2045857503 cites W2077609047 @default.
• W2045857503 cites W2079353098 @default.

• next