Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045862915> ?p ?o ?g. }
- W2045862915 endingPage "3117" @default.
- W2045862915 startingPage "3109" @default.
- W2045862915 abstract "Ligament tissue engineering based on cell-seeded biomechanically functional constructs is a commonly studied strategy toward native anterior cruciate ligament replacement. Little is known about the survival and differentiation of the seeded cells after the transplantation. We applied retroviral genetic marking to trace implanted cells and studied their differentiation by species-specific immunolabeling of the extracellular matrix produced. Goat bone marrow stromal cells were transduced with a MoMuLV-based vector encoding the ΔLNGFR gene. Transduced cells were seeded onto poly(lactic-co-glycolic acid) (PLGA) fibers and implanted subcutaneously into nude mice and left for various periods up to 6 weeks. Immunohistochemistry for LNGFR expression showed survival of the seeded cells after transplantation for up to 6 weeks. Immunohistochemistry for collagen type I and III showed the production of fibrous tissue inside the scaffolds. Moreover, using a goat-specific anti-collagen type III, donor-derived matrix could be demonstrated. We conclude that bone marrow stromal cells survived in vivo and at least partially differentiated after implantation." @default.
- W2045862915 created "2016-06-24" @default.
- W2045862915 creator A5015290220 @default.
- W2045862915 creator A5035897746 @default.
- W2045862915 creator A5057275242 @default.
- W2045862915 creator A5061661160 @default.
- W2045862915 creator A5077552107 @default.
- W2045862915 creator A5077647224 @default.
- W2045862915 creator A5079860342 @default.
- W2045862915 creator A5080107547 @default.
- W2045862915 creator A5090995592 @default.
- W2045862915 date "2009-10-01" @default.
- W2045862915 modified "2023-10-14" @default.
- W2045862915 title "In Vivo Matrix Production by Bone Marrow Stromal Cells Seeded on PLGA Scaffolds for Ligament Tissue Engineering" @default.
- W2045862915 cites W1552674655 @default.
- W2045862915 cites W1974486176 @default.
- W2045862915 cites W1977225005 @default.
- W2045862915 cites W1988106932 @default.
- W2045862915 cites W1997617677 @default.
- W2045862915 cites W2000156083 @default.
- W2045862915 cites W2000488306 @default.
- W2045862915 cites W2008029193 @default.
- W2045862915 cites W2024749377 @default.
- W2045862915 cites W2030667189 @default.
- W2045862915 cites W2030726962 @default.
- W2045862915 cites W2031297275 @default.
- W2045862915 cites W2031789487 @default.
- W2045862915 cites W2032785541 @default.
- W2045862915 cites W2034736027 @default.
- W2045862915 cites W2036647569 @default.
- W2045862915 cites W2037744155 @default.
- W2045862915 cites W2044786006 @default.
- W2045862915 cites W2048149237 @default.
- W2045862915 cites W2050380787 @default.
- W2045862915 cites W2050729770 @default.
- W2045862915 cites W2055502077 @default.
- W2045862915 cites W2056885025 @default.
- W2045862915 cites W2059277682 @default.
- W2045862915 cites W2062304147 @default.
- W2045862915 cites W2065173977 @default.
- W2045862915 cites W2065969745 @default.
- W2045862915 cites W2069847958 @default.
- W2045862915 cites W2071352906 @default.
- W2045862915 cites W2075262547 @default.
- W2045862915 cites W2081566702 @default.
- W2045862915 cites W2087659698 @default.
- W2045862915 cites W2093081023 @default.
- W2045862915 cites W2100994995 @default.
- W2045862915 cites W2102906606 @default.
- W2045862915 cites W2103805570 @default.
- W2045862915 cites W2112041130 @default.
- W2045862915 cites W2119204544 @default.
- W2045862915 cites W2140492768 @default.
- W2045862915 cites W2149242638 @default.
- W2045862915 cites W2149926088 @default.
- W2045862915 cites W2150295226 @default.
- W2045862915 cites W2151165961 @default.
- W2045862915 cites W2154177449 @default.
- W2045862915 cites W2165630004 @default.
- W2045862915 cites W2167642875 @default.
- W2045862915 cites W2235481750 @default.
- W2045862915 cites W2435514882 @default.
- W2045862915 cites W4255038051 @default.
- W2045862915 cites W4366658088 @default.
- W2045862915 doi "https://doi.org/10.1089/ten.tea.2008.0541" @default.
- W2045862915 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19338450" @default.
- W2045862915 hasPublicationYear "2009" @default.
- W2045862915 type Work @default.
- W2045862915 sameAs 2045862915 @default.
- W2045862915 citedByCount "9" @default.
- W2045862915 countsByYear W20458629152014 @default.
- W2045862915 countsByYear W20458629152016 @default.
- W2045862915 countsByYear W20458629152017 @default.
- W2045862915 countsByYear W20458629152020 @default.
- W2045862915 countsByYear W20458629152021 @default.
- W2045862915 crossrefType "journal-article" @default.
- W2045862915 hasAuthorship W2045862915A5015290220 @default.
- W2045862915 hasAuthorship W2045862915A5035897746 @default.
- W2045862915 hasAuthorship W2045862915A5057275242 @default.
- W2045862915 hasAuthorship W2045862915A5061661160 @default.
- W2045862915 hasAuthorship W2045862915A5077552107 @default.
- W2045862915 hasAuthorship W2045862915A5077647224 @default.
- W2045862915 hasAuthorship W2045862915A5079860342 @default.
- W2045862915 hasAuthorship W2045862915A5080107547 @default.
- W2045862915 hasAuthorship W2045862915A5090995592 @default.
- W2045862915 hasConcept C106487976 @default.
- W2045862915 hasConcept C136229726 @default.
- W2045862915 hasConcept C141071460 @default.
- W2045862915 hasConcept C142724271 @default.
- W2045862915 hasConcept C150903083 @default.
- W2045862915 hasConcept C16930146 @default.
- W2045862915 hasConcept C185592680 @default.
- W2045862915 hasConcept C189165786 @default.
- W2045862915 hasConcept C198826908 @default.
- W2045862915 hasConcept C202751555 @default.
- W2045862915 hasConcept C204232928 @default.
- W2045862915 hasConcept C207001950 @default.
- W2045862915 hasConcept C2780007613 @default.