FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045883905> ?p ?o ?g. }

• W2045883905 endingPage "3044" @default.
• W2045883905 startingPage "3034" @default.
• W2045883905 abstract "The orthodenticle-related protein (HpOtx) gene derived from the sea urchin Hemicentrotus pulcherrimus encodes two distinct isoforms, HpOtxE and HpOtxL, which are differentially expressed during early embryogenesis and are driven by TATA-less and TATA-containing promoters, respectively. In order to determine if the TATA element is involved in the establishment of the temporally specific expression profile of the HpOtx gene, reporter genes under the control of modified or wild-type HpOtxE/L promoters were introduced into fertilized eggs. When the activities of the different promoter constructs were examined, we found that deletion of the TATA element from the HpOtxL promoter causes early expression, whereas addition of the TATA element to the HpOtxE promoter causes delayed expression. This suppressive action of the TATA element on transcription from the HpOtxE/L promoters requires the presence of upstream CACGTG elements. These results indicate that the presence or absence of the TATA element determines, at least in part, the expression profile of the HpOtxE/L promoters, in concert with the transcription factor(s) that binds to the upstream CACGTG element. Immunoblot and gel retardation analyses suggest that functional interaction between CACGTG binding factor(s) and TATA factor(s) may be regulated by an unidentified third factor(s) during early embryogenesis in the sea urchin." @default.
• W2045883905 created "2016-06-24" @default.
• W2045883905 creator A5083145735 @default.
• W2045883905 date "2002-07-15" @default.
• W2045883905 modified "2023-10-15" @default.
• W2045883905 title "Functional interaction between TATA and upstream CACGTG elements regulates the temporally specific expression of Otx mRNAs during early embryogenesis of the sea urchin, Hemicentrotus pulcherrimus" @default.
• W2045883905 cites W1485413013 @default.
• W2045883905 cites W1525334014 @default.
• W2045883905 cites W1557101942 @default.
• W2045883905 cites W1852931409 @default.
• W2045883905 cites W1965905681 @default.
• W2045883905 cites W1969117475 @default.
• W2045883905 cites W1970063025 @default.
• W2045883905 cites W1972220069 @default.
• W2045883905 cites W1982685209 @default.
• W2045883905 cites W1996805085 @default.
• W2045883905 cites W1997302182 @default.
• W2045883905 cites W1999138582 @default.
• W2045883905 cites W2001318439 @default.
• W2045883905 cites W2006015474 @default.
• W2045883905 cites W2010141746 @default.
• W2045883905 cites W2012435045 @default.
• W2045883905 cites W2020060046 @default.
• W2045883905 cites W2022231372 @default.
• W2045883905 cites W2031710534 @default.
• W2045883905 cites W2036080788 @default.
• W2045883905 cites W2038699619 @default.
• W2045883905 cites W2039868825 @default.
• W2045883905 cites W2048370715 @default.
• W2045883905 cites W2050726666 @default.
• W2045883905 cites W2055465485 @default.
• W2045883905 cites W2062865836 @default.
• W2045883905 cites W2067700245 @default.
• W2045883905 cites W2083422367 @default.
• W2045883905 cites W2085730499 @default.
• W2045883905 cites W2087400681 @default.
• W2045883905 cites W2088503311 @default.
• W2045883905 cites W2090827398 @default.
• W2045883905 cites W2095612833 @default.
• W2045883905 cites W2098919421 @default.
• W2045883905 cites W2106882534 @default.
• W2045883905 cites W2122440217 @default.
• W2045883905 cites W2134381580 @default.
• W2045883905 cites W2134548041 @default.
• W2045883905 cites W2142890842 @default.
• W2045883905 cites W2147870129 @default.
• W2045883905 cites W2150049391 @default.
• W2045883905 cites W2150836531 @default.
• W2045883905 cites W2170117494 @default.
• W2045883905 cites W2182462737 @default.
• W2045883905 cites W2183073723 @default.
• W2045883905 cites W2209793704 @default.
• W2045883905 cites W2213536769 @default.
• W2045883905 cites W224702310 @default.
• W2045883905 cites W2254825490 @default.
• W2045883905 cites W2265015867 @default.
• W2045883905 cites W2289726584 @default.
• W2045883905 cites W2442033253 @default.
• W2045883905 cites W2888511473 @default.
• W2045883905 cites W350650882 @default.
• W2045883905 doi "https://doi.org/10.1093/nar/gkf439" @default.
• W2045883905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/135759" @default.
• W2045883905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12136085" @default.
• W2045883905 hasPublicationYear "2002" @default.
• W2045883905 type Work @default.
• W2045883905 sameAs 2045883905 @default.
• W2045883905 citedByCount "6" @default.
• W2045883905 crossrefType "journal-article" @default.
• W2045883905 hasAuthorship W2045883905A5083145735 @default.
• W2045883905 hasBestOaLocation W20458839051 @default.
• W2045883905 hasConcept C101762097 @default.
• W2045883905 hasConcept C104317684 @default.
• W2045883905 hasConcept C132376346 @default.
• W2045883905 hasConcept C138885662 @default.
• W2045883905 hasConcept C150194340 @default.
• W2045883905 hasConcept C153911025 @default.
• W2045883905 hasConcept C179926584 @default.
• W2045883905 hasConcept C192245184 @default.
• W2045883905 hasConcept C2776908312 @default.
• W2045883905 hasConcept C2780868196 @default.
• W2045883905 hasConcept C41895202 @default.
• W2045883905 hasConcept C53345823 @default.
• W2045883905 hasConcept C54355233 @default.
• W2045883905 hasConcept C65888428 @default.
• W2045883905 hasConcept C86339819 @default.
• W2045883905 hasConcept C86803240 @default.
• W2045883905 hasConcept C95444343 @default.
• W2045883905 hasConceptScore W2045883905C101762097 @default.
• W2045883905 hasConceptScore W2045883905C104317684 @default.
• W2045883905 hasConceptScore W2045883905C132376346 @default.
• W2045883905 hasConceptScore W2045883905C138885662 @default.
• W2045883905 hasConceptScore W2045883905C150194340 @default.
• W2045883905 hasConceptScore W2045883905C153911025 @default.
• W2045883905 hasConceptScore W2045883905C179926584 @default.
• W2045883905 hasConceptScore W2045883905C192245184 @default.
• W2045883905 hasConceptScore W2045883905C2776908312 @default.
• W2045883905 hasConceptScore W2045883905C2780868196 @default.
• W2045883905 hasConceptScore W2045883905C41895202 @default.

• next