Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045887549> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2045887549 endingPage "5468" @default.
- W2045887549 startingPage "5465" @default.
- W2045887549 abstract "Cyclopentadienyl half-sandwich ruthenium complexes have been demonstrated to be promising scaffolds as protein kinase inhibitors. In order to rapidly identify derivatives which display modified pharmacological properties, we developed the synthesis of an organoruthenium compound bearing an N-succinimidyl ester at the cyclopentadienyl moiety. The quenching of this activated ester with a library of primary amines, followed by testing of the resulting amide library, led to the identification of organometallic Pim-1 and GSK-3 inhibitors with improved potencies and kinase selectivities." @default.
- W2045887549 created "2016-06-24" @default.
- W2045887549 creator A5045543902 @default.
- W2045887549 creator A5080487872 @default.
- W2045887549 date "2006-11-01" @default.
- W2045887549 modified "2023-09-24" @default.
- W2045887549 title "Ruthenium Half-Sandwich Complexes as Protein Kinase Inhibitors: An <i>N</i>-Succinimidyl Ester for Rapid Derivatizations of the Cyclopentadienyl Moiety" @default.
- W2045887549 cites W1987938799 @default.
- W2045887549 cites W2006632173 @default.
- W2045887549 cites W2029432400 @default.
- W2045887549 cites W2059421295 @default.
- W2045887549 cites W2103268811 @default.
- W2045887549 cites W2125789563 @default.
- W2045887549 cites W2950026153 @default.
- W2045887549 doi "https://doi.org/10.1021/ol0620646" @default.
- W2045887549 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17107048" @default.
- W2045887549 hasPublicationYear "2006" @default.
- W2045887549 type Work @default.
- W2045887549 sameAs 2045887549 @default.
- W2045887549 citedByCount "73" @default.
- W2045887549 countsByYear W20458875492012 @default.
- W2045887549 countsByYear W20458875492013 @default.
- W2045887549 countsByYear W20458875492014 @default.
- W2045887549 countsByYear W20458875492015 @default.
- W2045887549 countsByYear W20458875492016 @default.
- W2045887549 countsByYear W20458875492017 @default.
- W2045887549 countsByYear W20458875492018 @default.
- W2045887549 countsByYear W20458875492019 @default.
- W2045887549 countsByYear W20458875492020 @default.
- W2045887549 countsByYear W20458875492021 @default.
- W2045887549 countsByYear W20458875492023 @default.
- W2045887549 crossrefType "journal-article" @default.
- W2045887549 hasAuthorship W2045887549A5045543902 @default.
- W2045887549 hasAuthorship W2045887549A5080487872 @default.
- W2045887549 hasConcept C121332964 @default.
- W2045887549 hasConcept C121745418 @default.
- W2045887549 hasConcept C161790260 @default.
- W2045887549 hasConcept C178790620 @default.
- W2045887549 hasConcept C181458950 @default.
- W2045887549 hasConcept C185592680 @default.
- W2045887549 hasConcept C21951064 @default.
- W2045887549 hasConcept C2776568683 @default.
- W2045887549 hasConcept C2778439535 @default.
- W2045887549 hasConcept C555196967 @default.
- W2045887549 hasConcept C62520636 @default.
- W2045887549 hasConcept C71240020 @default.
- W2045887549 hasConcept C91881484 @default.
- W2045887549 hasConceptScore W2045887549C121332964 @default.
- W2045887549 hasConceptScore W2045887549C121745418 @default.
- W2045887549 hasConceptScore W2045887549C161790260 @default.
- W2045887549 hasConceptScore W2045887549C178790620 @default.
- W2045887549 hasConceptScore W2045887549C181458950 @default.
- W2045887549 hasConceptScore W2045887549C185592680 @default.
- W2045887549 hasConceptScore W2045887549C21951064 @default.
- W2045887549 hasConceptScore W2045887549C2776568683 @default.
- W2045887549 hasConceptScore W2045887549C2778439535 @default.
- W2045887549 hasConceptScore W2045887549C555196967 @default.
- W2045887549 hasConceptScore W2045887549C62520636 @default.
- W2045887549 hasConceptScore W2045887549C71240020 @default.
- W2045887549 hasConceptScore W2045887549C91881484 @default.
- W2045887549 hasIssue "24" @default.
- W2045887549 hasLocation W20458875491 @default.
- W2045887549 hasLocation W20458875492 @default.
- W2045887549 hasOpenAccess W2045887549 @default.
- W2045887549 hasPrimaryLocation W20458875491 @default.
- W2045887549 hasRelatedWork W1604331706 @default.
- W2045887549 hasRelatedWork W1974317320 @default.
- W2045887549 hasRelatedWork W2002525719 @default.
- W2045887549 hasRelatedWork W2015865302 @default.
- W2045887549 hasRelatedWork W2029328232 @default.
- W2045887549 hasRelatedWork W2058374135 @default.
- W2045887549 hasRelatedWork W2062831929 @default.
- W2045887549 hasRelatedWork W2086013069 @default.
- W2045887549 hasRelatedWork W2953269826 @default.
- W2045887549 hasRelatedWork W3000107102 @default.
- W2045887549 hasVolume "8" @default.
- W2045887549 isParatext "false" @default.
- W2045887549 isRetracted "false" @default.
- W2045887549 magId "2045887549" @default.
- W2045887549 workType "article" @default.