Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045893119> ?p ?o ?g. }
- W2045893119 endingPage "103" @default.
- W2045893119 startingPage "97" @default.
- W2045893119 abstract "Chromobacterium violaceum is a Gram (−) bacteria found in water samples and soils from tropical and subtropical regions of the world. Violacein, the major pigment produced by these bacteria, has been shown to have antibiotic, antitumoral and trypanocidal activities. In the present work, the genotoxicity of violacein was investigated in four different cell lines by using the alkaline Comet assay and in VERO cells using the Micronucleus test. In the alkaline Comet assay, violacein, when tested at concentrations ranging from 0.19 to 1.5 μM, did not induce a significant increase in DNA damage in HEp-2 and MA104 cells. However, violacein was positive for DNA damage in FRhK-4 cells and for both DNA damage and micronuclei in VERO cells, in a concentration–response relationship. The results of this study indicated that violacein is genotoxic in VERO and FRhK-4 cells. These findings contribute to a comprehensive evaluation of the pharmacological potential of violacein." @default.
- W2045893119 created "2016-06-24" @default.
- W2045893119 creator A5022426537 @default.
- W2045893119 creator A5027163017 @default.
- W2045893119 creator A5045198892 @default.
- W2045893119 creator A5047307247 @default.
- W2045893119 creator A5063488407 @default.
- W2045893119 creator A5067822111 @default.
- W2045893119 date "2006-01-01" @default.
- W2045893119 modified "2023-10-18" @default.
- W2045893119 title "In vitro testing for genotoxicity of violacein assessed by Comet and Micronucleus assays" @default.
- W2045893119 cites W1587522833 @default.
- W2045893119 cites W1967331918 @default.
- W2045893119 cites W1980223650 @default.
- W2045893119 cites W1989991708 @default.
- W2045893119 cites W2005193114 @default.
- W2045893119 cites W2011732064 @default.
- W2045893119 cites W2015500565 @default.
- W2045893119 cites W2024264346 @default.
- W2045893119 cites W2028377177 @default.
- W2045893119 cites W2034469603 @default.
- W2045893119 cites W2036307672 @default.
- W2045893119 cites W2047161403 @default.
- W2045893119 cites W2059156332 @default.
- W2045893119 cites W2060286683 @default.
- W2045893119 cites W2066357142 @default.
- W2045893119 cites W2076632331 @default.
- W2045893119 cites W2092629964 @default.
- W2045893119 cites W2095413717 @default.
- W2045893119 cites W2098584111 @default.
- W2045893119 cites W2098883242 @default.
- W2045893119 cites W2102226960 @default.
- W2045893119 cites W2104000223 @default.
- W2045893119 cites W2114829464 @default.
- W2045893119 cites W2126902508 @default.
- W2045893119 cites W2152277794 @default.
- W2045893119 cites W2153115688 @default.
- W2045893119 cites W2154988239 @default.
- W2045893119 cites W2282446201 @default.
- W2045893119 cites W46770791 @default.
- W2045893119 doi "https://doi.org/10.1016/j.mrgentox.2005.11.001" @default.
- W2045893119 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16359912" @default.
- W2045893119 hasPublicationYear "2006" @default.
- W2045893119 type Work @default.
- W2045893119 sameAs 2045893119 @default.
- W2045893119 citedByCount "36" @default.
- W2045893119 countsByYear W20458931192012 @default.
- W2045893119 countsByYear W20458931192013 @default.
- W2045893119 countsByYear W20458931192014 @default.
- W2045893119 countsByYear W20458931192015 @default.
- W2045893119 countsByYear W20458931192016 @default.
- W2045893119 countsByYear W20458931192017 @default.
- W2045893119 countsByYear W20458931192018 @default.
- W2045893119 countsByYear W20458931192019 @default.
- W2045893119 countsByYear W20458931192020 @default.
- W2045893119 countsByYear W20458931192021 @default.
- W2045893119 countsByYear W20458931192022 @default.
- W2045893119 crossrefType "journal-article" @default.
- W2045893119 hasAuthorship W2045893119A5022426537 @default.
- W2045893119 hasAuthorship W2045893119A5027163017 @default.
- W2045893119 hasAuthorship W2045893119A5045198892 @default.
- W2045893119 hasAuthorship W2045893119A5047307247 @default.
- W2045893119 hasAuthorship W2045893119A5063488407 @default.
- W2045893119 hasAuthorship W2045893119A5067822111 @default.
- W2045893119 hasConcept C118687296 @default.
- W2045893119 hasConcept C143425029 @default.
- W2045893119 hasConcept C178790620 @default.
- W2045893119 hasConcept C185592680 @default.
- W2045893119 hasConcept C202751555 @default.
- W2045893119 hasConcept C2777916119 @default.
- W2045893119 hasConcept C2778959862 @default.
- W2045893119 hasConcept C2780358455 @default.
- W2045893119 hasConcept C29730261 @default.
- W2045893119 hasConcept C33618052 @default.
- W2045893119 hasConcept C36681516 @default.
- W2045893119 hasConcept C45080847 @default.
- W2045893119 hasConcept C523546767 @default.
- W2045893119 hasConcept C54355233 @default.
- W2045893119 hasConcept C552990157 @default.
- W2045893119 hasConcept C55493867 @default.
- W2045893119 hasConcept C58123911 @default.
- W2045893119 hasConcept C86803240 @default.
- W2045893119 hasConcept C89138240 @default.
- W2045893119 hasConcept C89423630 @default.
- W2045893119 hasConceptScore W2045893119C118687296 @default.
- W2045893119 hasConceptScore W2045893119C143425029 @default.
- W2045893119 hasConceptScore W2045893119C178790620 @default.
- W2045893119 hasConceptScore W2045893119C185592680 @default.
- W2045893119 hasConceptScore W2045893119C202751555 @default.
- W2045893119 hasConceptScore W2045893119C2777916119 @default.
- W2045893119 hasConceptScore W2045893119C2778959862 @default.
- W2045893119 hasConceptScore W2045893119C2780358455 @default.
- W2045893119 hasConceptScore W2045893119C29730261 @default.
- W2045893119 hasConceptScore W2045893119C33618052 @default.
- W2045893119 hasConceptScore W2045893119C36681516 @default.
- W2045893119 hasConceptScore W2045893119C45080847 @default.
- W2045893119 hasConceptScore W2045893119C523546767 @default.
- W2045893119 hasConceptScore W2045893119C54355233 @default.