FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045902181> ?p ?o ?g. }

• W2045902181 endingPage "356" @default.
• W2045902181 startingPage "350" @default.
• W2045902181 abstract "Background & AimsDespite prescription of gastroprotection among elderly nonsteroidal anti-inflammatory drug (NSAID) users, residual bleeding can still occur. We sought to determine the effect of proton pump inhibitors (PPI) on hospitalization and resource use among veterans in whom an upper gastrointestinal event (UGIE) occurred.MethodsWe identified from national pharmacy records veterans ≥65 years prescribed an NSAID, cyclooxygenase-2 selective NSAID (coxib), or salicylate (>325 mg/day) at any Veterans Affairs (VA) facility (01/01/00–12/31/04). Prescription fill data were linked longitudinally to a Veterans Affairs-Medicare dataset of inpatient, outpatient, and death files, and demographic and provider data. Among veterans in whom a UGIE occurred, we assessed the effect of prescription strategy on hospitalization, using a multivariate logistic regression model.ResultsA total of 3566 UGIEs occurred among a cohort that was predominantly male (97.5%), white (77%), with a mean age of 73.5 (SD, 5.7). Hospitalization occurred in 47.5%, and gastroprotection was associated with a 30% reduction in hospitalization compared with no PPI. Five-year pharmacy costs associated with the PPI strategy exceeded the no-PPI strategy ($742,406 vs $184,282); however, a substantial reduction in medical costs was observed with PPI ($9,948,738 vs $18,686,081).ConclusionsEven if an NSAID-UGIE occurs in the PPI-protected older veteran, the reduction in need for hospitalization results in a cost saving to the Department of Veterans Affairs. Despite prescription of gastroprotection among elderly nonsteroidal anti-inflammatory drug (NSAID) users, residual bleeding can still occur. We sought to determine the effect of proton pump inhibitors (PPI) on hospitalization and resource use among veterans in whom an upper gastrointestinal event (UGIE) occurred. We identified from national pharmacy records veterans ≥65 years prescribed an NSAID, cyclooxygenase-2 selective NSAID (coxib), or salicylate (>325 mg/day) at any Veterans Affairs (VA) facility (01/01/00–12/31/04). Prescription fill data were linked longitudinally to a Veterans Affairs-Medicare dataset of inpatient, outpatient, and death files, and demographic and provider data. Among veterans in whom a UGIE occurred, we assessed the effect of prescription strategy on hospitalization, using a multivariate logistic regression model. A total of 3566 UGIEs occurred among a cohort that was predominantly male (97.5%), white (77%), with a mean age of 73.5 (SD, 5.7). Hospitalization occurred in 47.5%, and gastroprotection was associated with a 30% reduction in hospitalization compared with no PPI. Five-year pharmacy costs associated with the PPI strategy exceeded the no-PPI strategy ($742,406 vs $184,282); however, a substantial reduction in medical costs was observed with PPI ($9,948,738 vs $18,686,081). Even if an NSAID-UGIE occurs in the PPI-protected older veteran, the reduction in need for hospitalization results in a cost saving to the Department of Veterans Affairs." @default.
• W2045902181 created "2016-06-24" @default.
• W2045902181 creator A5003848896 @default.
• W2045902181 creator A5037697618 @default.
• W2045902181 creator A5061971663 @default.
• W2045902181 date "2010-04-01" @default.
• W2045902181 modified "2023-10-11" @default.
• W2045902181 title "Reduced Hospitalization Cost for Upper Gastrointestinal Events That Occur Among Elderly Veterans Who Are Gastroprotected" @default.
• W2045902181 cites W10412033 @default.
• W2045902181 cites W1548435580 @default.
• W2045902181 cites W1928620804 @default.
• W2045902181 cites W1967313838 @default.
• W2045902181 cites W1967858966 @default.
• W2045902181 cites W1969927128 @default.
• W2045902181 cites W1979334802 @default.
• W2045902181 cites W1984878163 @default.
• W2045902181 cites W1985547591 @default.
• W2045902181 cites W1988343267 @default.
• W2045902181 cites W2000753724 @default.
• W2045902181 cites W2001350224 @default.
• W2045902181 cites W2004718890 @default.
• W2045902181 cites W2022630327 @default.
• W2045902181 cites W2022672351 @default.
• W2045902181 cites W2026478177 @default.
• W2045902181 cites W2034013987 @default.
• W2045902181 cites W2037640305 @default.
• W2045902181 cites W2047041406 @default.
• W2045902181 cites W2048622875 @default.
• W2045902181 cites W2057268557 @default.
• W2045902181 cites W2076605758 @default.
• W2045902181 cites W2080195394 @default.
• W2045902181 cites W2098216390 @default.
• W2045902181 cites W2099562325 @default.
• W2045902181 cites W2109715169 @default.
• W2045902181 cites W2117429908 @default.
• W2045902181 cites W2123533317 @default.
• W2045902181 cites W2129168200 @default.
• W2045902181 cites W2141951952 @default.
• W2045902181 cites W2330496155 @default.
• W2045902181 cites W2412935502 @default.
• W2045902181 cites W2610860323 @default.
• W2045902181 doi "https://doi.org/10.1016/j.cgh.2010.01.002" @default.
• W2045902181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20096378" @default.
• W2045902181 hasPublicationYear "2010" @default.
• W2045902181 type Work @default.
• W2045902181 sameAs 2045902181 @default.
• W2045902181 citedByCount "13" @default.
• W2045902181 countsByYear W20459021812012 @default.
• W2045902181 countsByYear W20459021812013 @default.
• W2045902181 countsByYear W20459021812014 @default.
• W2045902181 countsByYear W20459021812015 @default.
• W2045902181 countsByYear W20459021812018 @default.
• W2045902181 countsByYear W20459021812022 @default.
• W2045902181 crossrefType "journal-article" @default.
• W2045902181 hasAuthorship W2045902181A5003848896 @default.
• W2045902181 hasAuthorship W2045902181A5037697618 @default.
• W2045902181 hasAuthorship W2045902181A5061971663 @default.
• W2045902181 hasBestOaLocation W20459021811 @default.
• W2045902181 hasConcept C104863432 @default.
• W2045902181 hasConcept C126322002 @default.
• W2045902181 hasConcept C167135981 @default.
• W2045902181 hasConcept C194828623 @default.
• W2045902181 hasConcept C2426938 @default.
• W2045902181 hasConcept C2775969662 @default.
• W2045902181 hasConcept C2776345487 @default.
• W2045902181 hasConcept C2778451229 @default.
• W2045902181 hasConcept C2781025758 @default.
• W2045902181 hasConcept C512399662 @default.
• W2045902181 hasConcept C71924100 @default.
• W2045902181 hasConcept C98274493 @default.
• W2045902181 hasConceptScore W2045902181C104863432 @default.
• W2045902181 hasConceptScore W2045902181C126322002 @default.
• W2045902181 hasConceptScore W2045902181C167135981 @default.
• W2045902181 hasConceptScore W2045902181C194828623 @default.
• W2045902181 hasConceptScore W2045902181C2426938 @default.
• W2045902181 hasConceptScore W2045902181C2775969662 @default.
• W2045902181 hasConceptScore W2045902181C2776345487 @default.
• W2045902181 hasConceptScore W2045902181C2778451229 @default.
• W2045902181 hasConceptScore W2045902181C2781025758 @default.
• W2045902181 hasConceptScore W2045902181C512399662 @default.
• W2045902181 hasConceptScore W2045902181C71924100 @default.
• W2045902181 hasConceptScore W2045902181C98274493 @default.
• W2045902181 hasIssue "4" @default.
• W2045902181 hasLocation W20459021811 @default.
• W2045902181 hasLocation W20459021812 @default.
• W2045902181 hasOpenAccess W2045902181 @default.
• W2045902181 hasPrimaryLocation W20459021811 @default.
• W2045902181 hasRelatedWork W1996607884 @default.
• W2045902181 hasRelatedWork W2087473612 @default.
• W2045902181 hasRelatedWork W2118138430 @default.
• W2045902181 hasRelatedWork W2145276365 @default.
• W2045902181 hasRelatedWork W2476348678 @default.
• W2045902181 hasRelatedWork W2481872255 @default.
• W2045902181 hasRelatedWork W2606561216 @default.
• W2045902181 hasRelatedWork W2908601854 @default.
• W2045902181 hasRelatedWork W3161852304 @default.
• W2045902181 hasRelatedWork W4212794616 @default.
• W2045902181 hasVolume "8" @default.

• next