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- W2045937071 abstract "We report the cloning and sequencing of a cDNA from planarian Schmidtea polychroa (Platyhelminthes, Turbellaria, Tricladida) encoding for an unusual tubulin isoform (SpTub-1) which is specifically expressed in testis. Sequence comparison of SpTub-1 with other known tubulins reveals that it has the highest homology with alpha-tubulins, even though the analysis of the molecular features shows that this isoform is significantly divergent. Hybridization of SpTub-1 to restriction-digested genomic DNA to Southern blotting produced a multiple banding pattern indicating that in planarian, a tubulin multigene family exists. Using in situ hybridization, we showed that the transcript is specifically detectable in planarian testis, suggesting that it may play a role in spermatogenesis." @default.
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- W2045937071 date "2003-10-01" @default.
- W2045937071 modified "2023-09-27" @default.
- W2045937071 title "Molecular characterization and expression of a divergent α-tubulin in planarian Schmidtea polychroa" @default.
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- W2045937071 doi "https://doi.org/10.1016/s0167-4781(03)00159-3" @default.
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