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• W2045941692 abstract "The localization of the rat brain 5-HTIA receptor mRNA was analyzed by RNAse mapping and in situ hybridization during postnatal development, particularly in the cerebellum. The regional distribution of 5-HTIA mRNA during the first 2 postnatal weeks was different from that found in adults. In some areas of the immature brain (hippocampus, cerebral cortex), 5-HTIA mRNA was found in lower density than in the adult brain. In contrast, high concentrations of the transcript were present in other brain structures only during the first days after birth. Thus, in the cerebellum, the density of 5-HTIA mRNA decreased markedly from day 2 to day 9 after birth and could hardly be detected in the adult animal. The localization of the mRNA in the molecular/Purkinje cell layer of the immature cerebellum agreed with that of the 5-HTIA receptor protein visualized by immmunocytochemistry and was consistent with the hypothesis that Purkinje cells express this receptor." @default.
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• W2045941692 date "1994-07-01" @default.
• W2045941692 modified "2023-09-29" @default.
• W2045941692 title "Postnatal development and localization of 5-HTIA receptor mRNA in rat forebrain and cerebellum" @default.
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• W2045941692 doi "https://doi.org/10.1016/0165-3806(94)90099-x" @default.
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