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• W2045962788 endingPage "571" @default.
• W2045962788 startingPage "557" @default.
• W2045962788 abstract "A wide spectrum of auto-immune manifestations is frequently reported in non-Hodgkin's lymphoma (NHL). The purpose of the review is to describe the immune manifestations observed in NHL, according to their histological subtype and to discuss the current physiopathological hypothesis with their therapeutic relevance.Most of the organs can be targeted by an immune process due to the lymphoproliferative disease: they include skin diseases (paraneoplastic pemphigus, vasculitis, urticaria, acrosyndromes), peripheral and central nervous system involvement (polyneuropathy, multifocal neuropathy), haematological manifestations (immune cytopenia, acquired bleeding disorders), rheumatologic diseases (arthritis, systemic vasculitis, myositis) and renal lesion (cryoglobulinemia, glomerulopathies). A higher prevalence of autoantibodies, such as antinuclear antibodies, Antiphospholipid antibodies, or endomysium antibodies, is observed in NHL but usually without clinical manifestations. In B-cell NHL, clinical and biological immune manifestations are more frequently observed in indolent lymphoma than in aggressive NHL. In T-cell NHL, immune manifestations are frequent and polymorphous, preceding usually the diagnosis of lymphoma. The prognosis value of the immune manifestations in NHL is unclear. Immune manifestations can be also be related to the treatment procedure, including fludarabine, Interferon, autograft or Rituximab. The physiopathology of the immune manifestations may involve auto-antibodies production by natural CD5+ autoreactive B-cell from which is issue the proliferation, a lost of immune tolerance, an abnormality in the Fas/Fas Ligand pathway or a chronic antigenic stimulation.As observed in T-cell lymphoma cases, immunosuppressive treatment can control both immune manifestations and lymphoproliferation, suggesting that lymphoma and auto-immunity may be the two aspects of the same process. The monoclonal antibody anti-CD20 (rituximab), able to suppress the tumoral cells and change the B-cell repertoire is the most promising treatment to cure immune disorders related to NHL. So far, rituximab has been successfully used in mixed cryoglobulinemia and cold agglutinins secondary to NHL." @default.
• W2045962788 created "2016-06-24" @default.
• W2045962788 creator A5003078312 @default.
• W2045962788 creator A5037857352 @default.
• W2045962788 creator A5082700087 @default.
• W2045962788 date "2005-07-01" @default.
• W2045962788 modified "2023-10-13" @default.
• W2045962788 title "Manifestations dysimmunitaires associées aux lymphomes" @default.
• W2045962788 cites W1482062495 @default.
• W2045962788 cites W1488086007 @default.
• W2045962788 cites W1524345877 @default.
• W2045962788 cites W1524930492 @default.
• W2045962788 cites W1548460291 @default.
• W2045962788 cites W1588486949 @default.
• W2045962788 cites W1588719784 @default.
• W2045962788 cites W1916527093 @default.
• W2045962788 cites W1926113248 @default.
• W2045962788 cites W1963725668 @default.
• W2045962788 cites W1963775236 @default.
• W2045962788 cites W1964654190 @default.
• W2045962788 cites W1965659966 @default.
• W2045962788 cites W1970359325 @default.
• W2045962788 cites W1971290145 @default.
• W2045962788 cites W1972867177 @default.
• W2045962788 cites W1974382447 @default.
• W2045962788 cites W1974885851 @default.
• W2045962788 cites W1975163576 @default.
• W2045962788 cites W1977147254 @default.
• W2045962788 cites W1978276885 @default.
• W2045962788 cites W1978974255 @default.
• W2045962788 cites W1982921859 @default.
• W2045962788 cites W1984036881 @default.
• W2045962788 cites W1984550182 @default.
• W2045962788 cites W1985305596 @default.
• W2045962788 cites W1989124008 @default.
• W2045962788 cites W1989157151 @default.
• W2045962788 cites W1990437716 @default.
• W2045962788 cites W1994542857 @default.
• W2045962788 cites W1995813515 @default.
• W2045962788 cites W1998136765 @default.
• W2045962788 cites W2000260473 @default.
• W2045962788 cites W2000671641 @default.
• W2045962788 cites W2003425504 @default.
• W2045962788 cites W2004449806 @default.
• W2045962788 cites W2009138741 @default.
• W2045962788 cites W2010303502 @default.
• W2045962788 cites W2012873002 @default.
• W2045962788 cites W2014150221 @default.
• W2045962788 cites W2015414702 @default.
• W2045962788 cites W2016511376 @default.
• W2045962788 cites W2017113742 @default.
• W2045962788 cites W2017497764 @default.
• W2045962788 cites W2018614236 @default.
• W2045962788 cites W2020532274 @default.
• W2045962788 cites W2021830136 @default.
• W2045962788 cites W2024065457 @default.
• W2045962788 cites W2026901410 @default.
• W2045962788 cites W2027637969 @default.
• W2045962788 cites W2027921255 @default.
• W2045962788 cites W2032031168 @default.
• W2045962788 cites W2039894743 @default.
• W2045962788 cites W2040179365 @default.
• W2045962788 cites W2040800789 @default.
• W2045962788 cites W2041166899 @default.
• W2045962788 cites W2041297457 @default.
• W2045962788 cites W2041482161 @default.
• W2045962788 cites W2041755534 @default.
• W2045962788 cites W2043144666 @default.
• W2045962788 cites W2043974250 @default.
• W2045962788 cites W2044628656 @default.
• W2045962788 cites W2045002823 @default.
• W2045962788 cites W2045487014 @default.
• W2045962788 cites W2046761837 @default.
• W2045962788 cites W2046900942 @default.
• W2045962788 cites W2046991549 @default.
• W2045962788 cites W2054775610 @default.
• W2045962788 cites W2057118004 @default.
• W2045962788 cites W2057160290 @default.
• W2045962788 cites W2057176304 @default.
• W2045962788 cites W2060041600 @default.
• W2045962788 cites W2061177011 @default.
• W2045962788 cites W2062470158 @default.
• W2045962788 cites W2063653871 @default.
• W2045962788 cites W2065788928 @default.
• W2045962788 cites W2067733904 @default.
• W2045962788 cites W2069030127 @default.
• W2045962788 cites W2070008464 @default.
• W2045962788 cites W2070662174 @default.
• W2045962788 cites W2073531991 @default.
• W2045962788 cites W2075187924 @default.
• W2045962788 cites W2077144817 @default.
• W2045962788 cites W2077524046 @default.
• W2045962788 cites W2078092364 @default.
• W2045962788 cites W2079547995 @default.
• W2045962788 cites W2089995122 @default.
• W2045962788 cites W2090525833 @default.
• W2045962788 cites W2090799281 @default.
• W2045962788 cites W2093846994 @default.

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