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- W2045976659 abstract "Cyanoacetic acid derivatives are the starting materials for a plethora of multicomponent reaction (MCR) scaffolds. Herein, we describe scope of a valuable general protocol for the synthesis of arrays of 2-aminoquinoline-3-carboxamides from cyanoacetamides and 2-aminobenzaldehydes or heterocyclic derivatives via a Friedländer reaction variation. In many cases, the reactions involve a very convenient work up by simple precipitation and filtration. More than 40 new products are described. We foresee our protocol and the resulting derivatives becoming very valuable to greatly expanding the scaffold space of cyanoacetamide derivatives." @default.
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- W2045976659 date "2012-04-18" @default.
- W2045976659 modified "2023-09-25" @default.
- W2045976659 title "Cyanoacetamides (IV): Versatile One-Pot Route to 2-Quinoline-3-carboxamides" @default.
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- W2045976659 doi "https://doi.org/10.1021/co3000133" @default.
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