FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045988032> ?p ?o ?g. }

• W2045988032 endingPage "1578" @default.
• W2045988032 startingPage "1571" @default.
• W2045988032 abstract "A new class of 1 beta-methylcarbapenems bearing a doubly quaternarized 1,4-diazabicyclooctane (DABCO) substituted dithiocarbamate moiety at the C-2 side chain was prepared, and the biological profiles of the compounds, including in vitro and in vivo anti-MRSA activity and DHP-I susceptibility, were evaluated to identify a carbapenem derivative that was superior to BO-3482 (1). As a result, we discovered a 1 beta-methyl-2-[4-(4-carbamoylmethyl-1,4-diazabicyclo[2,2,2]octanediium-1-yl)methyl-1,2,3,6-tetrahydropyridinylthiocarbonylthio]carbapenem, 14a showing greater than 2-fold better anti-MRSA activity in a mouse infection model and 3-fold better DHP-I susceptibility as compared with BO-3482 (1)." @default.
• W2045988032 created "2016-06-24" @default.
• W2045988032 creator A5003575852 @default.
• W2045988032 creator A5015649518 @default.
• W2045988032 creator A5017141269 @default.
• W2045988032 creator A5023739413 @default.
• W2045988032 creator A5031936902 @default.
• W2045988032 creator A5032056639 @default.
• W2045988032 creator A5032143684 @default.
• W2045988032 creator A5032633970 @default.
• W2045988032 creator A5052356083 @default.
• W2045988032 creator A5054984833 @default.
• W2045988032 creator A5079568135 @default.
• W2045988032 creator A5082028578 @default.
• W2045988032 creator A5087562396 @default.
• W2045988032 creator A5089761965 @default.
• W2045988032 creator A5089855988 @default.
• W2045988032 date "2001-06-01" @default.
• W2045988032 modified "2023-10-12" @default.
• W2045988032 title "Dicationic dithiocarbamate carbapenems with anti-MRSA activity" @default.
• W2045988032 cites W1617345819 @default.
• W2045988032 cites W1965478714 @default.
• W2045988032 cites W1972349129 @default.
• W2045988032 cites W1985508970 @default.
• W2045988032 cites W2003379019 @default.
• W2045988032 cites W2013782013 @default.
• W2045988032 cites W2023819367 @default.
• W2045988032 cites W2036658163 @default.
• W2045988032 cites W2039622890 @default.
• W2045988032 cites W2052087768 @default.
• W2045988032 cites W2061387719 @default.
• W2045988032 cites W2077904083 @default.
• W2045988032 cites W2087485426 @default.
• W2045988032 cites W2125235782 @default.
• W2045988032 cites W2157029049 @default.
• W2045988032 cites W2949715498 @default.
• W2045988032 cites W2950180354 @default.
• W2045988032 cites W2951043620 @default.
• W2045988032 cites W2951486464 @default.
• W2045988032 cites W4254533003 @default.
• W2045988032 doi "https://doi.org/10.1016/s0968-0896(01)00044-x" @default.
• W2045988032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11408176" @default.
• W2045988032 hasPublicationYear "2001" @default.
• W2045988032 type Work @default.
• W2045988032 sameAs 2045988032 @default.
• W2045988032 citedByCount "66" @default.
• W2045988032 countsByYear W20459880322012 @default.
• W2045988032 countsByYear W20459880322013 @default.
• W2045988032 countsByYear W20459880322014 @default.
• W2045988032 countsByYear W20459880322015 @default.
• W2045988032 countsByYear W20459880322016 @default.
• W2045988032 countsByYear W20459880322017 @default.
• W2045988032 countsByYear W20459880322018 @default.
• W2045988032 countsByYear W20459880322019 @default.
• W2045988032 countsByYear W20459880322020 @default.
• W2045988032 countsByYear W20459880322021 @default.
• W2045988032 countsByYear W20459880322022 @default.
• W2045988032 countsByYear W20459880322023 @default.
• W2045988032 crossrefType "journal-article" @default.
• W2045988032 hasAuthorship W2045988032A5003575852 @default.
• W2045988032 hasAuthorship W2045988032A5015649518 @default.
• W2045988032 hasAuthorship W2045988032A5017141269 @default.
• W2045988032 hasAuthorship W2045988032A5023739413 @default.
• W2045988032 hasAuthorship W2045988032A5031936902 @default.
• W2045988032 hasAuthorship W2045988032A5032056639 @default.
• W2045988032 hasAuthorship W2045988032A5032143684 @default.
• W2045988032 hasAuthorship W2045988032A5032633970 @default.
• W2045988032 hasAuthorship W2045988032A5052356083 @default.
• W2045988032 hasAuthorship W2045988032A5054984833 @default.
• W2045988032 hasAuthorship W2045988032A5079568135 @default.
• W2045988032 hasAuthorship W2045988032A5082028578 @default.
• W2045988032 hasAuthorship W2045988032A5087562396 @default.
• W2045988032 hasAuthorship W2045988032A5089761965 @default.
• W2045988032 hasAuthorship W2045988032A5089855988 @default.
• W2045988032 hasConcept C106159729 @default.
• W2045988032 hasConcept C111771559 @default.
• W2045988032 hasConcept C114373084 @default.
• W2045988032 hasConcept C150903083 @default.
• W2045988032 hasConcept C155647269 @default.
• W2045988032 hasConcept C162324750 @default.
• W2045988032 hasConcept C178790620 @default.
• W2045988032 hasConcept C185592680 @default.
• W2045988032 hasConcept C193042331 @default.
• W2045988032 hasConcept C202751555 @default.
• W2045988032 hasConcept C207001950 @default.
• W2045988032 hasConcept C2775995839 @default.
• W2045988032 hasConcept C2776131168 @default.
• W2045988032 hasConcept C2776568683 @default.
• W2045988032 hasConcept C2776624427 @default.
• W2045988032 hasConcept C2776685102 @default.
• W2045988032 hasConcept C2777545050 @default.
• W2045988032 hasConcept C2779631663 @default.
• W2045988032 hasConcept C501593827 @default.
• W2045988032 hasConcept C55493867 @default.
• W2045988032 hasConcept C71240020 @default.
• W2045988032 hasConcept C86803240 @default.
• W2045988032 hasConcept C94665300 @default.
• W2045988032 hasConceptScore W2045988032C106159729 @default.

• next